Sökning: "neurokemi och neurotoxikologi"

Visar resultat 1 - 5 av 25 avhandlingar innehållade orden neurokemi och neurotoxikologi.

  1. 1. Applications of multi-component condensations and development of polyamine synthesis on solid-phase

    Detta är en avhandling från Stockholm : Department of Neurochemistry and Neurotoxicology, Stockholm University

    Författare :Daniel Jönsson; Stockholms universitet.; [2002]
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Neurochemistry and Neurotoxicology; neurokemi och neurotoxikologi;

    Sammanfattning : Solid-phase synthesis of small non-polymeric molecules has become increasingly important as a tool in the development of pharmacologically active compounds. Of particular interest are the syntheses of compounds with low molecular weight, low polarity and a reduced flexibility of the functional groups, i.e. LÄS MER

  2. 2. On inflammatory cytokines and β-amyloid peptides in acute and chronic neurodegeneration

    Detta är en avhandling från Stockholm : Department of Neurochemistry and Neurotoxicology, Stockholm University

    Författare :Roya Tehranian; Stockholms universitet.; [2001]
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Inflammation; Cytokines; Amyloid; Peptides; Nerve degeneration; Neurochemistry and Neurotoxicology; neurokemi och neurotoxikologi;

    Sammanfattning : Insults to the brain as well as neurodegenerative diseases are known to elicit inflammatory responses. Inflammation in the brain can on one hand initiate processes that are harmful to the injured tissue and exacerbate the damage, leading to neuronal degeneration and glial activation, and on the other hand activate processes that may be necessary for repair mechanisms and regeneration. LÄS MER

  3. 3. Design and evaluation of drug delivery vehicles

    Detta är en avhandling från Stockholm : Institutionen för neurokemi

    Författare :Caroline Palm Apergi; Stockholms universitet.; [2008]
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICINE Chemistry Neurochemistry; MEDICIN Kemi Neurokemi; Neurochemistry and Neurotoxicology; neurokemi och neurotoxikologi;

    Sammanfattning : A crucial aspect of drug delivery is efficient transport to the site of action. Thus, there is a need to design and evaluate new delivery vehicles. In this thesis two delivery vehicles, cell-penetrating peptides and bacterial ghosts, were evaluated. LÄS MER

  4. 4. Alzheimer Aβ peptides induce dysregulation of C/EBP and NF-кB in glial cells

    Detta är en avhandling från Stockholm : Institutionen för neurokemi

    Författare :Malin Samuelsson; Stockholms universitet.; [2008]
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Alzheimer s disease; amyloid-β; astrocytes; C EBP; glia; microglia; neuroinflammation; NF-кB; MEDICINE Chemistry Neurochemistry; MEDICIN Kemi Neurokemi; Neurochemistry and Neurotoxicology; neurokemi och neurotoxikologi;

    Sammanfattning : Inflammation is believed to contribute to neurodegeneration in Alzheimer’s disease (AD). AD in turn is believed to be a consequence of accumulated amyloid-β (Aβ) peptides, that subsequently form senile plaques, due to imbalance between production and clearance of Aβ. LÄS MER

  5. 5. Development of Novel Transport Peptides and Their Application in Antisense Techniques

    Detta är en avhandling från Stockholm : Institutionen för neurokemi

    Författare :Ursel Soomets; Stockholms universitet.; [1999]
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICINE Chemistry Neurochemistry; MEDICIN Kemi Neurokemi; neurokemi och neurotoxikologi; Neurochemistry and Neurotoxicology;

    Sammanfattning : .... LÄS MER