Sökning: "vasopressin"

Visar resultat 26 - 30 av 67 avhandlingar innehållade ordet vasopressin.

  1. 26. Pharmacokinetic and pharmacodynamic analysis of antidiuretic peptides

    Författare :Torbjörn Callréus; Avdelningen för klinisk kemi och farmakologi; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; lithium; indirect-response model; pharmacodynamics; pharmacokinetics; gastrointestinal absorption; gastrointestinal motility; loperamide; erythromycin; antidiuretic effect; desmopressin; overhydration; vasopressin analogue F992 ; interaction; Pharmacological sciences; pharmacognosy; pharmacy; toxicology; Farmakologi; farmakognosi; farmaci; toxikologi;

    Sammanfattning : The clinical pharmacology of desmopressin and a new vasopressin analogue (F992) was investigated in healthy human subjects. The common procedure of overhydration of healthy volunteers when studying the antidiuretic effect of a drug, may affect the pharmacokinetics, in particular the volumes of distribution. LÄS MER

  3. 27. The effects of some peptide hormones on osteoblast-like cells : with specific focus on oxytocin and vasopressin

    Författare :Alena Lagumdzija; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :h0B; SaOS-2; OXT; AVP; IGF-I; PTH; PTHrP; eNOSKO;

    Sammanfattning : The nonapeptides oxytocin (OXT) and vasopressin (AVP) are mainly produced in the hypothalamus and released into the circulation through the neurohypophysis. Recently, an OXT-receptor was demonstrated in human osteoblast-like (hOB) cells, and it has been suggested that patients with central diabetes insipidus (deficiency of AVP) have decreased bone mass. LÄS MER

  4. 28. Postoperative nausea and vomiting in women : an unglamorous aspect of anaesthesia

    Författare :Eva Oddby Muhrbeck; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :Anaesthesia; blood glucose; clonidine; epinephrine; pathophysiology; platelet count; postoperative nausea and vomiting; serotonin; therapeutic suggestion; vasopressin; women.;

    Sammanfattning : Postoperative nausea and vomiting (PONY) still remains a common and undesirable side effect of anaesthesia. Women are afflicted by PONY two to three times more often than men and a substantial number of patients consider PONV to be the worst part of the entire surgical procedure. LÄS MER

  5. 29. Microdialysis sampling from skeletal muscle and adipose tissue with special reference to the effects of insulin on tissue blood flow and glucose metabolism

    Författare :Hans Rosdahl; Jan Henriksson; Urban Ungerstedt; Keith N. Frayn; Karolinska Institutet Inst. för fysiologi och farmakologi; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :microdialysis; insulin; skeletal muscle; adipose tissue; glucose; amino acids; MEDICINE; MEDICIN; Key words: microdialysis; human; skeletal muscle; adipose tissue; ethanol; insulin; glucose; lactate; glycerol; urea; amino acids; adrenaline; isoprenaline; adenosine; vasopressin; microcirculation; dextran; colloid osmotic pressure; isometric exercise;

    Sammanfattning : .... LÄS MER

  7. 30. Leptin targets in the brain regulating body weight : receptors and down-stream mediators of leptin in neurons of the hypothalamus and brainstem

    Författare :Marie-Louise Håkansson Ovesjö; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :AGRP; antibody; arcuate nucleus; blood-brain-barrier; body weight; brainstem; CART; CRH; DMX; food intake; GABA; GAD; galanin; hypothalamus; immunohistochemistry; in situ hybridization; lateral hypothalamic area; leptin; leptin receptor; MCH; NPY; obesity; Ob-R; Ob-Rb; oxytocin; paraventricular nucleus; POMC; somatostatin; serotonin; STAT3; supraoptic nucleus; transcription factor; vasopressin; VGAT;

    Sammanfattning : Obesity is a disease which has become a global epidemic that is beginning to replace undernutrition and infectious diseases as the most significant contributor to ill health in the world. In particular, obesity is associated with diabetes mellitus, hypertension and coronary heart disease. LÄS MER