Sökning: "overhydration"

Hittade 2 avhandlingar innehållade ordet overhydration.

1. 1. Pharmacokinetic and pharmacodynamic analysis of antidiuretic peptides

   Författare :Torbjörn Callréus; Avdelningen för klinisk kemi och farmakologi; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; lithium; indirect-response model; pharmacodynamics; pharmacokinetics; gastrointestinal absorption; gastrointestinal motility; loperamide; erythromycin; antidiuretic effect; desmopressin; overhydration; vasopressin analogue F992 ; interaction; Pharmacological sciences; pharmacognosy; pharmacy; toxicology; Farmakologi; farmakognosi; farmaci; toxikologi;

   Sammanfattning : The clinical pharmacology of desmopressin and a new vasopressin analogue (F992) was investigated in healthy human subjects. The common procedure of overhydration of healthy volunteers when studying the antidiuretic effect of a drug, may affect the pharmacokinetics, in particular the volumes of distribution. LÄS MER

3. 2. Evaluation of Myocardial Function in Chronic Kidney Disease : A Colour Tissue Velocity Imaging Study

   Författare :Shirley Hayashi; Lars-Åke Brodin; Svend Aakhus; KTH; []
   Nyckelord :Cardiac; Kidney; Tissue; Velocity; MEDICINE; MEDICIN;

   Sammanfattning : In patients with chronic kidney disease (CKD), overhydration, uremic toxins and left ventricular (LV) dyssynchrony are factors that may lead to LV dysfunction and conduction abnormalities and thus contribute to the high cardiac mortality. Colour tissue velocity imaging (TVI) allows a detailed quantitative analysis of cardiac function in CKD patients, opening new possibilities to evaluate longitudinal myocardial motion, rapid isovolumetric events, LV filling pressure and LV synchronicity. LÄS MER