Sökning: "CRH"

Visar resultat 1 - 5 av 25 avhandlingar innehållade ordet CRH.

  1. 1. Winter Depression: Clinical, Psychosocial and Biochemical Characteristics

    Författare :Baba Pendse; Lund Psykiatri; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; NPY.; Psychiatry; clinical psychology; psychosomatics; Psykiatri; klinisk psykologi; psykosomatik; CRH; Social characteristics; Psychopathology; Temperament; Nonseasonal major depression; Suicide attempt; Winter depression; SAD;

    Sammanfattning : Seasonal Affective Disorder with depressive episodes during the autumn/winter seasons (winter depression) is common. Outpatients with winter depression were studied regarding temperament, psychopathology, social characteristics, psychosocial functioning and the neuropeptides corticotropin - releasing hormone (CRH) and neuropeptide Y (NPY), which are known to be involved in stress-regulation. LÄS MER

  3. 2. Central and Peripheral Neuroendocrine Factors in Cancer-Associated Anorexia and Cachexia

    Författare :Jonathan R Burgos; Göteborgs universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; cancer anorexia-cachexia syndrome; inflammation; TSH receptor; cocaine- and amphetamine-regulated transcript; nesfatin-1; CRH; hypothalamus; brainstem; MCG101;

    Sammanfattning : Cancer anorexia-cachexia syndrome (CACS) develops in response to tumor-host biochemical interactions. A loss of appetite (anorexia) and increased metabolism results in a progressive wasting of adipose and skeletal muscle tissues (cachexia). LÄS MER

  4. 3. Epigenetic dysregulation in relation to psychiatric traits in adolescence and adulthood

    Författare :Adrian Desai Boström; Helgi B. Schiöth; Daniel Nätt; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; methylome-wide; DNA methylation; hypersexual disorder; microRNA; oxytocin signaling; psychiatry; hsa-miR-4456; microRNA-4456; MIR4456; epigenetic dysregulation; microRNA expression; gene target prediction; epigenetics; suicide; suicide attempt; HPA axis; CRH gene; Epigenetics; Methylation; Adolescent depression; MIR4646; methylome-wide association study; Omega-3; mQTL analysis; GAD1; HDAC3; DAWBA;

    Sammanfattning : Epigenetics has evolved into a key research focus in the field of psychiatry. DNA methylation is the most researched epigenetic mechanism. In paper I-III, 130 and 93 adolescents were randomly recruited at two separate intervals. LÄS MER

  5. 4. Preterm and term cervical ripening : studies on CRH, HMGB1, toll-like receptors, cytokines and matrix metalloproteinases

    Författare :Aurelija Dubicke; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :Cervical fibroblasts; cervical ripening; cervix; chemokines; cytokines; CRH; HMGB1; interleukin; labor; preterm; preterm labor; matrix metalloproteinases; pregnancy; PPROM; Tolllike receptors;

    Sammanfattning : Objective: Preterm birth (PTB) is the leading cause of neonatal mortality and morbidity. Despite the existing treatment, the frequency of PTB has not changed in the past thirty years. Incomplete understanding of the biological and pathophysiological mechanisms underlying preterm delivery is the major obstacle to preventing PTB. LÄS MER

  7. 5. Life-charting patients with treatment-refractory affective disorder

    Författare :Anna Ehnvall; Göteborgs universitet; []
    Nyckelord :Life charting; treatment-refractory affective disorder; sensitisation; ; CRH challenge test; ACTH; MHPG; perception of parental rearing;

    Sammanfattning : Introduction:In treatment-refractory affective illness there are several hypothesis to suggest alterations in the neurobiological systems in relation to illness course. The underlying mechanisms have been scantily investigated. LÄS MER