Sökning: "MCH"

Visar resultat 1 - 5 av 26 avhandlingar innehållade ordet MCH.

1. 1. Avian MHC : Characterization and expression patterns of classical and non-classical MHC-I genes

   Författare :Anna Drews; MEMEG; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; MCH class I; Classical genes; Non-classical genes; Expression; Passerine birds;

   Sammanfattning : The function of the vertebrate immune system is to enable recognition and elimination of microorganisms that can cause harm (pathogens). A key component in adaptive immunity is the major histocompatibility complex (MHC) that codes for molecules with antigen presentation function. LÄS MER

3. 2. Hypothalamic neuronal circuits involved in the regulation of food intake and body weight : histochemical studies in lean rats and obese mutant mice

   Författare :Matilda Bäckberg; Karolinska Institutet; Karolinska Institutet; []
   Nyckelord :AGRP; arcuate nucleus; BBB; CART; GABA; GABA receptors; immunohistochemistry; in situ hybridization; hypothalamus; LHA; leptin; MCH; NPY; orexin; POMC; tubby;

   Sammanfattning : Obesity is a major health problem because of its dramatic increase in prevalence and its association with type 2 diabetes, coronary heart diseases, hypertension and stroke. It is well known that signals generated in response to feeding behavior are integrated in the brain. LÄS MER

4. 3. Brain control of energy balance : localization and regulation of proteins involved in the central control of food intake and body weight

   Författare :Maria Collin; Karolinska Institutet; Karolinska Institutet; []
   Nyckelord :AGRP; arcuate nucleus; brainstem; CART; GABA; Glutamate; GPCR; habenular complex; immunohistochemistry; in situ hybridization; hypothalamus; leptin; leptin receptor; LHA; MCH; NPY; Ob-Rb; POMC; serotonin; STAT3; transporter; ventromedial hypothalamic nucleus; VGLUT1-3.;

   Sammanfattning : Obesity has become a worldwide threat to human well-being and is now so common that it is beginning to replace undernutrition and infectious disease as the most significant contributor to ill health. Obesity increases the risk for aquiring serious diseases such as diabetes type 2, hypertension, coronary heart disease and certain forms of cancer. LÄS MER

5. 4. Leptin targets in the brain regulating body weight : receptors and down-stream mediators of leptin in neurons of the hypothalamus and brainstem

   Författare :Marie-Louise Håkansson Ovesjö; Karolinska Institutet; Karolinska Institutet; []
   Nyckelord :AGRP; antibody; arcuate nucleus; blood-brain-barrier; body weight; brainstem; CART; CRH; DMX; food intake; GABA; GAD; galanin; hypothalamus; immunohistochemistry; in situ hybridization; lateral hypothalamic area; leptin; leptin receptor; MCH; NPY; obesity; Ob-R; Ob-Rb; oxytocin; paraventricular nucleus; POMC; somatostatin; serotonin; STAT3; supraoptic nucleus; transcription factor; vasopressin; VGAT;

   Sammanfattning : Obesity is a disease which has become a global epidemic that is beginning to replace undernutrition and infectious diseases as the most significant contributor to ill health in the world. In particular, obesity is associated with diabetes mellitus, hypertension and coronary heart disease. LÄS MER

7. 5. Melanophore a2-Adrenoceptors

   Författare :Samuel Svensson; Susanna Cotecchia; Linköpings universitet; []
   Nyckelord :MEDICINE; MEDICIN;

   Sammanfattning : The present study provides new insight into the pharmacology, the signal transduction mechanisms and the molecular biology of a2-adrenoceptors (a2-ARs) in black pigment cells (melanophores) of a teleost fish, the cuckoo wrasse (Labrus ossifagus L.). LÄS MER