Sökning: "vascular density"

Visar resultat 1 - 5 av 117 avhandlingar innehållade orden vascular density.

1. 1. Implantation-Site Dependent Differences in Engraftment and Function of Transplanted Pancreatic Islets

   Författare :Joey Lau; Per-Ola Carlsson; Leif Jansson; Carina Carlsson; Caroline Kampf; Annika Tibell; Uppsala universitet; []
   Nyckelord :Cell biology; Type 1 diabetes; pancreatic islets; human islets; islet transplantation; vascular engraftment; revascularization; implantation-site; microenvironment; vascular density; insulin release; pro insulin biosynthesis; glucose oxidation; Cellbiologi;

   Sammanfattning : Transplanting pancreatic islets into the liver through the portal vein is currently the most common procedure in clinical islet transplantations for treating patients with brittle type 1 diabetes. However, most islet grafts fail within a 5-year period necessitating retransplantation. LÄS MER

3. 2. Vascular density and bone marrow fibrosis in childhood acute lymphoblastic leukemia

   Författare :Ulrika Norén Nyström; Anders Bergh; Erik Forestier; Göran Roos; Henrik Schrøder; Umeå universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Childhood acute lymphoblastic leukemia; microvessel density; bone marrow fibrosis; in vitro drug resistance; minimal residual disease; outcome; Oncology; Onkologi;

   Sammanfattning : Background: In childhood acute lymphoblastic leukemia (ALL), the cure rate has now reached 80% in the western world. Even so, 15¬–20% will die from the disease or treatment-related causes, among them children who did not present any known unfavorable features at diagnosis. LÄS MER

4. 3. Vascular receptor changes in ischemic stroke

   Författare :Emelie Stenman; Lund Medicin; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Vascular receptor changes; Ischemic stroke; Endothelin; Angiotensin; Cardiovascular system; Kardiovaskulära systemet; Pharmacological sciences; pharmacognosy; pharmacy; farmakognosi; farmaci; toxikologi; toxicology; Farmakologi;

   Sammanfattning : The present thesis aimed to examine how ischemic stroke affects the vascular endothelin and angiotensin systems in cerebral arteries. To study vascular receptor changes in ischemic stroke transient focal ischemia was induced in rats. LÄS MER

5. 4. Experimental Studies on the Vasculature of Endogenous and Transplanted Islets of Langerhans

   Författare :Göran Mattsson; Leif Jansson; Alberto Hayek; Uppsala universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Medicine; islets of Langerhans; endothelial cells; islet transplantation; vascular density; diabetes mellitus; Medicin; Dermatology and venerology; clinical genetics; internal medicine; Dermatologi och venerologi; klinisk genetik; invärtesmedicin;

   Sammanfattning : The blood vessels of the pancreatic islets are of crucial importance for oxygen and metabolite supply as well as dispersal of secreted hormones. In addition to this, endothelial cells have an important role in the revascularization process after islet transplantation. LÄS MER

7. 5. Functional genomics of vascular endothelial cells

   Författare :Elisabet Wallgard; Karolinska Institutet; Karolinska Institutet; []
   Nyckelord :Vasculature; endothelial cells; angiogenesis; vascular endothelial growth factor VEGF ; Notch; transcriptome; genomics; microarray; tumor; retina; morpholino knockdown;

   Sammanfattning : Angiogenesis, the formation of new blood vessels from preexisting ones, is a process involved in normal development as well as in several pathological conditions, such as cancer, ischemic heart disease, wound healing and certain retinal complications. Antiangiogenic targeting is therefore a promising new therapeutic principle. LÄS MER