Sökning: "microenvironment"
Visar resultat 1 - 5 av 238 avhandlingar innehållade ordet microenvironment.
1. Imaging the tumor microenvironment the dynamics and modification of hypoxia
Detta är en avhandling från Umeå : StrålningsvetenskaperSammanfattning : The tumor vasculature is poor and heterogeneous which may result in inadequate oxygenation and changed energy status. In addition the balance between cell proliferation and the rate of cell death is disturbed, which results in tumor growth. LÄS MER
2. Targeting the prostate tumor microenvironment and vasculature the role of castration, tumor-associated macrophages and pigment epithelium-derived factor
Detta är en avhandling från Umeå : Medicinsk biovetenskapSammanfattning : BACKGROUND: Prostate cancer is the most common cancer among Swedish men. For patients with metastatic prostate cancer the standard therapy is castration, a treatment that initially provides symptomatic relief but unfortunately is not curative. New therapeutic targets for advanced prostate cancer are therefore needed. LÄS MER
3. Adaptive mechanisms in the hypoxic tumor microenvironment. Functional role of proteoglycans and identification of potential treatment targets
Detta är en avhandling från Lund University: Faculty of MedicineSammanfattning : Cancer cells reside in a complex microenvironment comprising stromal cells and immune cells embedded in an extracellular matrix (ECM). Early on in tumor progression, cells reach a critical volume beyond which blood supply is impaired, leading to a decrease in oxygen levels (hypoxia) and nutrient supply. LÄS MER
4. Studies of the tumor microenvironment Local and systemic effects exerted by the cross-talk between tumor and stroma cells in pancreatic cancer
Detta är en avhandling från Linköping : Linköping University Electronic PressSammanfattning : Pancreatic cancer is one of the most lethal cancers and despite all research efforts the last 50 years, there are still no effective therapy for this terrible disease. Until quite recently most research in the field of pancreatic duct adenocarcinoma (PDAC) was focused on the tumor cells and mechanisms essential for their proliferation and survival. LÄS MER
5. Growth factor signaling in the breast tumor microenvironment
Detta är en avhandling från Lund University: Faculty of MedicineSammanfattning : Cancer represents a collection of malignancies characterized by an aberrant expansion of cells. This unrestrained growth is the result of the acquisition of several pro-survival features and the evasion of cellular fail-safe mechanisms, collectively known as the hallmarks of cancer. LÄS MER
