Sökning: "bone marrow fibrosis"
Visar resultat 1 - 5 av 9 avhandlingar innehållade orden bone marrow fibrosis.
1. Hyaluronan in normal and malignant bone marrow : a clinical and morphological study with emphasis on myelofibrosis
Sammanfattning : Fibrosis in the bone marrow is usually denominated myelofibrosis and may contribute to impaired hematopoiesis. Myelofibrosis is seen both in malignant and non-malignant diseases. LÄS MER
2. Vascular density and bone marrow fibrosis in childhood acute lymphoblastic leukemia
Sammanfattning : Background: In childhood acute lymphoblastic leukemia (ALL), the cure rate has now reached 80% in the western world. Even so, 15¬–20% will die from the disease or treatment-related causes, among them children who did not present any known unfavorable features at diagnosis. LÄS MER
3. Human Bone Marrow Microenvironment in Health and Disease
Sammanfattning : Hematopoietic stem cells (HSCs) are safeguarded from various threats such as stress, injury, or radiationwithin specialized microenvironments or niches within the bone marrow. In this thesis, we investigatedvarious facets of the bone marrow (BM) microenvironment and its critical role in hematopoiesis andrelated disorders. LÄS MER
4. Development of new MRl-based analysis methods for improved diagnosis of low back pain patients
Sammanfattning : BACKGROUND Low back pain (LBP) is the leading cause of disability worldwide, where three of four individuals experience back pain at some point in their lives. The pathophysiological background of LBP is probably multifactorial, where bone marrow damage, tissue changes in the vertebral endplates, and intervertebral disc (IVD) degeneration have been recognized as tissue changes linked to pain. LÄS MER
5. Mesenchymal stromal cells in lung tissue
Sammanfattning : Mesenchymal stromal cells (MSC) are multipotent cells with immunomodulatory and regenerative properties. During recent years, the interest in using MSC for clinical approaches for various diseases have increased. LÄS MER