Sökning: "genomics"

Visar resultat 1 - 5 av 267 avhandlingar innehållade ordet genomics.

  1. 1. Speciation genomics : A perspective from vertebrate systems

    Författare :Nagarjun Vijay; Jochen. B.W Wolf; C. Alex Buerkle; Uppsala universitet; []
    Nyckelord :evolution; speciation; genomics; vertebrate; adaptation; selection; linked selection; crow; killer whale; hybrid zone; transcriptomics; population genetics; behaviour; colouration; Biology with specialization in Evolutionary Genetics; Biologi med inriktning mot evolutionär genetik;

    Sammanfattning : Species are vital entities in biology. Species are generally considered to be discrete entities, consisting of a group of (usually interbreeding) individuals that are similar in phenotype and genetic composition, yet differ in significant ways from other species. LÄS MER

  2. 2. On the Origins of mobile Antibiotic Resistance Genes : A comparative genomics approach

    Författare :Stefan Ebmeyer; Göteborgs universitet; Göteborgs universitet; Gothenburg University; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICAL AND HEALTH SCIENCES; antibiotic resistance; comparative genomics; bacterial genomics; antibiotic resistance genes;

    Sammanfattning : Mobile antibiotic resistance genes (ARGs), transferable between bacterial cells, are major contributors to the antibiotic resistance crisis we are facing today. From which organisms pathogens acquired these genes is mostly unknown, yet knowledge about their origin is needed in order to limit the emergence and spread of novel ARGs in the future. LÄS MER

  3. 3. Evolutionary genomics in Corvids : – From single nucleotides to structural variants

    Författare :Matthias H. Weissensteiner; Jochen B.W. Wolf; Manfred Grabherr; Kateryna M. Makova; Uppsala universitet; []
    Nyckelord :NATURAL SCIENCES; NATURVETENSKAP; NATURVETENSKAP; NATURAL SCIENCES; evolutionary genetics; genomics; population genetics; selection; recombination; chromosomal features; colouration; insertion; deletion; inversion; crow; tandem repeat; transposable element; gene expression;

    Sammanfattning : Heritable genetic variation is the raw material of evolution and can occur in many different forms, from altering single nucleotides to rearranging stretches of millions at once. DNA mutations that result in phenotypic differences are the basis upon which natural selection can act, leading to a shift of the frequency of those mutations. LÄS MER

  4. 4. Complex disease genetics : Utilising targeted sequencing and homogeneous ancestry

    Författare :Argyri Mathioudaki; Kerstin Lindblad-Toh; Panagiotis Deloukas; Uppsala universitet; []
    Nyckelord :NATURAL SCIENCES; NATURVETENSKAP; NATURVETENSKAP; NATURAL SCIENCES; ankylosing spondylitis; breast cancer; targeted sequencing; Sweden; genetics; population stratification.; Molekylär genetik; Molecular Genetics;

    Sammanfattning : The complex disease investigations presented in this thesis aimed to provide new information regarding underlying genetics by using targeted sequencing and ethnically homogeneous cohorts. This work moved past current methodologies and addressed data stratification issues, that might have been hindering new findings. LÄS MER

  5. 5. Genomics of Arbuscular Mycorrhizal Fungi : Expanding knowledge, one assembly at a time

    Författare :Merce Montoliu-Nerin; Anna Rosling; Hanna Johannesson; Nicolas Corradi; Uppsala universitet; []
    Nyckelord :NATURAL SCIENCES; NATURVETENSKAP; NATURVETENSKAP; NATURAL SCIENCES; genomics; arbuscular mycorrhizal fungi; phylogenomics; DNA; evolution; Bioinformatics; Bioinformatik; Biologi med inriktning mot molekylär evolution; Biology with specialization in Molecular Evolution;

    Sammanfattning : Most life forms that inhabit Earth today are still unknown or are difficult to study. Accessing their DNA can give us information of their biology, ecology, and evolution, even when unculturable. The research here presented focused on method development for genomic research of non-model organisms. LÄS MER