Sökning: "genomics"

Visar resultat 1 - 5 av 273 avhandlingar innehållade ordet genomics.

  1. 1. Speciation genomics A perspective from vertebrate systems

    Detta är en avhandling från Uppsala : Acta Universitatis Upsaliensis

    Författare :Nagarjun Vijay; Uppsala universitet.; [2016]
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; evolution; speciation; genomics; vertebrate; adaptation; selection; linked selection; crow; killer whale; hybrid zone; transcriptomics; population genetics; behaviour; colouration; Biology with specialization in Evolutionary Genetics; Biologi med inriktning mot evolutionär genetik;

    Sammanfattning : Species are vital entities in biology. Species are generally considered to be discrete entities, consisting of a group of (usually interbreeding) individuals that are similar in phenotype and genetic composition, yet differ in significant ways from other species. LÄS MER

  2. 2. Evolutionary genomics in Corvids – From single nucleotides to structural variants

    Detta är en avhandling från Uppsala : Acta Universitatis Upsaliensis

    Författare :Matthias H. Weissensteiner; Jochen B.W. Wolf; Manfred Grabherr; Kateryna M. Makova; [2019]
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; evolutionary genetics; genomics; population genetics; selection; recombination; chromosomal features; colouration; insertion; deletion; inversion; crow; tandem repeat; transposable element; gene expression;

    Sammanfattning : Heritable genetic variation is the raw material of evolution and can occur in many different forms, from altering single nucleotides to rearranging stretches of millions at once. DNA mutations that result in phenotypic differences are the basis upon which natural selection can act, leading to a shift of the frequency of those mutations. LÄS MER

  3. 3. Molecular Subtypes of Melanoma. Biological and Clinical Significance

    Detta är en avhandling från Lund University: Faculty of Medicine

    Författare :Helena Cirenajwis; Lund University.; Lunds universitet.; Lund University.; Lunds universitet.; Lund University.; Lunds universitet.; [2016]
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Melanoma; molecular subtypes; gene expression; next generation sequencing;

    Sammanfattning : Cutaneous malignant melanoma (CMM) is the most lethal form of skin cancer and its incidence has increased faster than that of any other cancer, rendering it a major public health problem worldwide. High-throughput screenings have opened the door to a new scientific world, which enables molecular-based characterization of large cancer cohort collections. LÄS MER

  4. 4. Adaptive divergence in fission yeast From experimental evolution to evolutionary genomics

    Detta är en avhandling från Uppsala : Acta Universitatis Upsaliensis

    Författare :Sergio Ivan Tusso Gomez; Uppsala universitet.; [2019]
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; adaptation; divergence; selection; experimental evolution; genomics; genome evolution; population genetics; fission yeast; phenotypic variation; Biology with specialization in Evolutionary Genetics; Biologi med inriktning mot evolutionär genetik;

    Sammanfattning : How adaptation and population differentiation occur is fundamental to understand the origin of biodiversity. Work in speciation alongside the increased ease of generating genomic data have allowed the exploration of genomic changes relevant to adaptation. LÄS MER

  5. 5. Comparative Genomics in Diplomonads Lifestyle Variations Revealed at Genetic Level

    Detta är en avhandling från Uppsala : Acta Universitatis Upsaliensis

    Författare :Feifei Xu; Uppsala universitet.; [2015]
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; comparative genomics; Giardia intestinalis; Spironucleus salmonicida; Trepomonas; diplomonad; intestinal parasite; free-living; sexual recombination; hydrogenosome; horizontal gene transfer; Biologi med inriktning mot molekylär evolution; Biology with specialization in Molecular Evolution;

    Sammanfattning : As sequencing technologies advance genome studies are becoming a basic tool for studying an organism, and with more genomes available comparative genomics is maturing into a powerful tool for biological research. This thesis demonstrates the strength of a comparative genomics approach on a group of understudied eukaryotes, the diplomonads. LÄS MER