Sökning: "Vascular receptor changes"

Visar resultat 1 - 5 av 80 avhandlingar innehållade orden Vascular receptor changes.

  1. 1. Vascular receptor changes in ischemic stroke

    Författare :Emelie Stenman; Lund Medicin; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Vascular receptor changes; Ischemic stroke; Endothelin; Angiotensin; Cardiovascular system; Kardiovaskulära systemet; Pharmacological sciences; pharmacognosy; pharmacy; farmakognosi; farmaci; toxikologi; toxicology; Farmakologi;

    Sammanfattning : The present thesis aimed to examine how ischemic stroke affects the vascular endothelin and angiotensin systems in cerebral arteries. To study vascular receptor changes in ischemic stroke transient focal ischemia was induced in rats. LÄS MER

  3. 2. Vascular Endothelin and Angiotensin Receptors Regulation in Inflammatory Arterial Disorders

    Författare :Ivan Dimitrijevic; Lund Medicin; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; ischemic heart disease; resistance artery; giant cell arteritis; temporal artery; immunohistochemistry; AT2 receptor; AT1 receptor; Endothelin-1; ETA receptor; ETB receptor;

    Sammanfattning : The present thesis is aimed to examine the hypothesis that the degree of vascular inflammation correlates with the expression of vascular endothelin and angiotensin receptors. The receptor changes were studied in subcutaneous resistance arteries in patients with different degrees of ischemic heart disease (IHD). LÄS MER

  4. 3. Vascular Effects of P2 Receptors. Changes in Congestive Heart Failure

    Författare :Malin Malmsjö; Lund Medicin; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; congestive heart failure; pyrimidine; purine; P2 receptor; vasodilatation; vasoconstriction; hyperpolarisation; EDHF; NO; Vascular; endothelium; Cardiovascular system; Kardiovaskulära systemet;

    Sammanfattning : Extracellular nucleotides induce dilatation and constriction of blood vessels by activation of P2 receptors. In this thesis the vasomotor effects of P2 receptor activation were studied in the rat mesenteric artery, and their changes in congestive heart failure (CHF) were evaluated using in vitro pharmacology, electrophysiology and competitive RT-PCR. LÄS MER

  5. 4. Endothelin receptor changes during inflammation in the lung

    Författare :Bengt Granström; Lund Pediatrik; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Andningsorganen; Respiratory system; Upregulation; Smooth muscle cells; Smoking; Sephadex; Remodeling; Rat; mRNA; Human; ETB receptor; ETA receptor; Lung; Endothelin; Asthma bronchiale; Contraction;

    Sammanfattning : Endothelin-1 (ET-1) is an extremely potent smooth muscle spasmogen well known from the vascular system but also active within the airways. The importance of its proinflammatory and co-mitogenic properties has become increasingly evident, the endothelin system also having been shown to mimic the signal features of asthma, COPD and other pulmonary diseases. LÄS MER

  7. 5. Stroke, Sex and Vascular Receptor Changes in the Brain

    Författare :Hilda Ahnstedt; Lund Medicin; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; endothelin receptors; Cerebral ischemia; sex; estrogen; progesterone; sex differences; human cerebral arteries; endothelin-1; angiotensin II; middle cerebral artery occlusion; extra-cellular signal regulated kinase 1 and 2;

    Sammanfattning : Stroke is a severe cerebrovascular disease in which the neuronal tissue and vasculature of the brain undergo ischemia-evoked alterations. We have demonstrated an increased expression of cerebrovascular contractile receptors in the brain. This is hypothesized to mitigate cerebral blood flow and exacerbate tissue damage after stroke. LÄS MER