Sökning: "Endothelin"

Visar resultat 1 - 5 av 110 avhandlingar innehållade ordet Endothelin.

  1. 1. Endothelin receptor changes during inflammation in the lung

    Detta är en avhandling från Laboratory of Experimental Vascular Research Department of Clinical Sciences Lund University

    Författare :Bengt Granström; Lund University.; Lunds universitet.; [2006]
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Andningsorganen; Respiratory system; Upregulation; Smooth muscle cells; Smoking; Sephadex; Remodeling; Rat; mRNA; Human; ETB receptor; ETA receptor; Lung; Endothelin; Asthma bronchiale; Contraction;

    Sammanfattning : Endothelin-1 (ET-1) is an extremely potent smooth muscle spasmogen well known from the vascular system but also active within the airways. The importance of its proinflammatory and co-mitogenic properties has become increasingly evident, the endothelin system also having been shown to mimic the signal features of asthma, COPD and other pulmonary diseases. LÄS MER

  2. 2. Modulation of the Progenitor Cell and Homeostatic Capacities of Müller Glia Cells in Retina Focus on α2-Adrenergic and Endothelin Receptor Signaling Systems

    Detta är en avhandling från Uppsala : Acta Universitatis Upsaliensis

    Författare :Mohammad Harun-Or-Rashid; Uppsala universitet.; [2016]
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Alpha2-adrenergic receptor; Brimonidine; Brn3a; Dedifferentiation; Endothelin; EGFR; ERK1 2; Neuroprotection; NMDA; MIO-M1 human Müller cell; Müller cells; Retina; Retinal ganglion cells; Src-kinase; Transactivation.; Medical Science; Medicinsk vetenskap;

    Sammanfattning : Müller cells are major glial cells in the retina and have a broad range of functions that are vital for the retinal neurons. During retinal injury gliotic response either leads to Müller cell dedifferentiation and formation of a retinal progenitor or to maintenance of mature Müller cell functions. LÄS MER

  3. 3. Importance of MAPK and PKC in cerebrovascular endothelin receptor changes

    Detta är en avhandling från Department of Clinical Sciences, Lund University

    Författare :Marie Henriksson; Lund University.; Lunds universitet.; [2006]
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; farmakognosi; farmaci; toxikologi; toxicology; pharmacy; pharmacognosy; Pharmacological sciences; Kardiovaskulära systemet; Cardiovascular system; Fysiologi; Physiology; cerebral arteries; ischemia; receptors; endothelin; Farmakologi;

    Sammanfattning : Endothelin is a vasoactive peptide that exerts its effect through two receptors; the endothelin type A (ETA) and type B (ETB) receptor. The contractile ETA receptor is localized on smooth muscle cells in the vascular wall, while the ETB receptors are mainly situated on endothelial cells, mediating vasodilatation. LÄS MER

  4. 4. Altered expression of contractile endothelin receptors in the vascular bed

    Detta är en avhandling från Department of Cell and Organism Biology, Lund University

    Författare :Mikael Adner; Lund University.; Lunds universitet.; [1998]
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Cardiovascular system; upregulation; transcriptional regulation; smooth muscle cells; plasticity; organ culture; Endothelin; receptor; Kardiovaskulära systemet;

    Sammanfattning : This thesis aims at characterizing the endothelin (ET) receptors in different vascular beds of man and rat. The ET-A receptor was shown to be the only contractile ET receptor present in all vascular regions, with the exception of the rat mesenteric vein where a weak ET-B receptor-mediated contraction was seen. LÄS MER

  5. 5. Endothelin and endothelin receptors in human pregnancy and delivery

    Detta är en avhandling från Stockholm : Karolinska Institutet, false

    Författare :Kerstin Wolff; Karolinska Institutet.; Karolinska Institutet.; [1996]
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Endothelin; endothelin receptor; human; pregnancy; preeclampsia; delivery;

    Sammanfattning : From the Division of Clinical Science, Department of Obstetrics and Gynecology, Karolinska Institute, Huddinge University Hospital, Stockholm, Sweden. Endothelin and Endothelin-Receptors in Human Pregnancy and Delivery Kerstin Wolff Background: Endothelin -1 (ET-1) is a 21-amino acid peptide, first described by Yanagisawa et al in 1988. LÄS MER