Sökning: "Joey Lau"
Hittade 5 avhandlingar innehållade orden Joey Lau.
1. Functional Impairments of Islets Transplanted into the liver
Sammanfattning : .... LÄS MER
2. Implantation-Site Dependent Differences in Engraftment and Function of Transplanted Pancreatic Islets
Sammanfattning : Transplanting pancreatic islets into the liver through the portal vein is currently the most common procedure in clinical islet transplantations for treating patients with brittle type 1 diabetes. However, most islet grafts fail within a 5-year period necessitating retransplantation. LÄS MER
3. Engraftment of Pancreatic Islets in Alternative Transplantation Sites and the Feasibility of in vivo Monitoring of Native and Transplanted Beta-Cell Mass
Sammanfattning : Islet transplantation is a possible curative treatment for type 1 diabetes (T1D). Currently the liver dominates as implantation site, despite the many challenges encountered at this site.Acute hypoxia in islets transplanted to muscle and omentum, two possible alternative sites, was prevailing. LÄS MER
4. Transplantation of stem cell-derived islets as a treatment for type 1 diabetes
Sammanfattning : Type 1 diabetes (T1D) is an autoimmune disease that leads to an immune attack on insulin-producing beta cells, necessitating lifelong insulin therapy. For individuals with brittle diabetes and poor metabolic control, the option of pancreatic human islet transplantation exists. LÄS MER
5. The Impact of Pancreatic Islet Vascular Heterogeneity on Beta Cell Function and Disease
Sammanfattning : Diabetes Mellitus is a group of complex and heterogeneous metabolic disorders characterized by hyperglycemia. Even though the condition has been extensively studied, its causes and complex pathologies are still not fully understood. The occurring damage to the pancreatic islets is strikingly heterogeneous. LÄS MER