Sökning: "toll-like receptor 4"
Visar resultat 11 - 15 av 52 avhandlingar innehållade orden toll-like receptor 4.
11. Preterm and term cervical ripening : studies on CRH, HMGB1, toll-like receptors, cytokines and matrix metalloproteinases
Sammanfattning : Objective: Preterm birth (PTB) is the leading cause of neonatal mortality and morbidity. Despite the existing treatment, the frequency of PTB has not changed in the past thirty years. Incomplete understanding of the biological and pathophysiological mechanisms underlying preterm delivery is the major obstacle to preventing PTB. LÄS MER
12. Role of Neutrophils and Innate Immune Mechanisms in Urinary Tract Infections
Sammanfattning : Urinary tract infections (UTI) are among the most common infections in man. Despite their prevalence, information on the molecular mechanisms defects that explain the increased susceptibility to disease are lacking. LÄS MER
13. Acute pancreatitis, from local defense to remote organ injury
Sammanfattning : Acute pancreatitis (AP) is an inflammatory disease of the pancreas. Acute abdominal pain is the most common symptom. Pancreatic injury is mild in 80% of patients, who recover without complications. The remaining patients have a severe disease with local and systemic complications such as acute lung injury (ALI). LÄS MER
14. Harnessing the immunoregulatory capacity of single-stranded oligonucleotides to modulate innate immunity
Sammanfattning : As the first line of defense, the innate immune system is exceptionally efficacious against invading pathogens but must be tightly regulated to avoid immune-related pathogenesis. Accordingly, the innate immune system recognizes highly conserved components associated with infections and damaged cells using a limited number of pattern-recognition receptors (PRRs), which are differentially expressed across cell types. LÄS MER
15. Influence of maternal allergy on the intra uterine environment and on immune functions of the neonate
Sammanfattning : The prevalence of IgE mediated allergic diseases has drastically increased during the past few decades and there is no satisfactory explanation. A family history of allergic disease is clearly a strong risk factor, bin in view of the rapidity of the increase in allergy prevalence environmental factors are likely to have played a crucial role. LÄS MER