Sökning: "matrix metalloproteinases"

Visar resultat 1 - 5 av 68 avhandlingar innehållade orden matrix metalloproteinases.

  1. 1. Matrix metalloproteinases in Helicobacter inducedgastritis

    Författare :Philip Bergin; Göteborgs universitet.; Gothenburg University.; Göteborgs universitet.; Gothenburg University.; [2004]
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Helicobacter pylori; Helicobacter felis; Matrix metalloproteinase; macrophage; Gastritis;

    Sammanfattning : Helicobacter pylori infects the stomach and areas of gastric metaplasia in the duodenum. Theinfection leads to peptic ulcers or gastric cancers in 10-20% of infected individuals, while themajority are more or less asymptomatic. However, active chronic gastritis develops in all infectedindividuals, often in association with atrophic gastritis. LÄS MER

  2. 2. Towards surgical use of matrix metalloproteinase biology

    Detta är en avhandling från Linköping University Electronic Press

    Författare :Björn Pasternak; Linköpings universitet.; Linköpings universitet.; [2008]
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Achilles tendon; colon; tetracyclines; tissue inhibitor of metalloproteinases TIMP ; wound healing.; colorectal surgery; extracellular matrix; humans; matrix metalloproteinases MMPs ; rats; surgical anastomosis; sutures; tendon injuries; MEDICINE Surgery Surgical research Orthopaedics; MEDICIN Kirurgi Kirurgisk forskning Ortopedi;

    Sammanfattning : Matrix metalloproteinases (MMPs), such as collagenases, are a family of enzymes capable of degrading most constituents of the extracellular matrix. MMPs are thought to be involved in the aetiopathogenesis of tendon rupture. Additionally, failure of healing has in some instances been associated with elevated levels of MMPs. LÄS MER

  3. 3. Effects of sex steroids and tamoxifen on matrix metalloproteinase activity and generation of endostatin in the breast

    Detta är en avhandling från Institutionen för biomedicin och kirurgi

    Författare :Ulrika W. Nilsson; Linköpings universitet.; Linköpings universitet.; [2007]
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Angiogenesis; Breast cancer; TGF-β1; Endostatin; Estradiol; Mammary gland; Matrix metalloproteinases; MCF-7; Microdialysis; Nude mice; Tamoxifen; MEDICINE Surgery Oncology; MEDICIN Kirurgi Onkologi;

    Sammanfattning : Sex steroids are inevitable in women. However, long-term exposure to sex steroids increases the risk of breast cancer. A complete understanding of sex steroid control of the breast and how it relates to breast cancer risk is still lacking. LÄS MER

  4. 4. Matrix metalloproteinases and their inhibitors in ocular neovascularization

    Detta är en avhandling från Stockholm : Karolinska Institutet, Department of Clinical Sciences

    Författare :Björn Steén; Karolinska Institutet.; Karolinska Institutet.; [2004]
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Angiogenesis; Neovascularization; Retina; Bruch membrane; Cornea; MMP; TIMP; VEGF; In situ hybridization.;

    Sammanfattning : Growth of pathological new vessels (angiogenesis) in the eye is a leading cause of severe vision-loss. Ocular angiogenesis is seen in the anterior part of the eye as in corneal neovascularization, or in the posterior part as in diabetic retinopathy, retinopathy of prematurity or age-related macular degeneration. LÄS MER

  5. 5. Migration on extracellular matrix surface and infiltration into matrix - two distinguishable activities of human T cells

    Detta är en avhandling från Stockholm : Karolinska Institutet, Department of Clinical Sciences

    Författare :Jyrki Ivanoff; Umeå universitet.; [2003]
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Immunology; extracellular matrix; fibronectin; collagen type IV; laminin; neuropeptide; chemokine; TIMP-1; MMP-9; T cells; Migration; Immunologi; MEDICINE Microbiology; immunology; infectious diseases Immunology; MEDICIN Mikrobiologi; immunologi; infektionssjukdomar Immunologi; Clinical Immunology; klinisk immunologi;

    Sammanfattning : Migration of T-lymphocytes on a surface coated with extracellular matrix (ECM) components (two-dimensional (2-D) migration) and migration (infiltration) into a matrix (Three-dimesional (3-D) migration) are complex events and the underlying mechanisms are not yet fully understood. Here 2-D and 3-D migration were studied by use of seven leukemic T-cell lines representing discrete differentiation stages, a non-leukemic T-cell clone, and normal peripheral blood T cells. LÄS MER