Sökning: "Jenny Hallgren Martinsson"

Hittade 3 avhandlingar innehållade orden Jenny Hallgren Martinsson.

  1. 1. A Search for the Masked Mechanism Behind IgG-Mediated Suppression of Antibody Responses

    Författare :Joakim Bergström; Birgitta Heyman; Jenny Hallgren Martinsson; Frida Henningsson Johnson; Mats Bemark; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; FcγR; complement; sheep erythrocytes; IgG-mediated immune suppression; rhesus prophylaxis; rhesus D antigen; germinal center; Immunologi; Immunology;

    Sammanfattning : Antibodies passively administered together with their specific antigen can enhance or suppress the specific antibody response. This phenomenon is known as antibody feedback regulation. Whether this modulation causes up- or downregulation of the antibody response depends both on the antibody isotype and the antigen used. LÄS MER

  3. 2. Harnessing the immunoregulatory capacity of single-stranded oligonucleotides to modulate innate immunity

    Författare :Aleksandra Dondalska; Anna-Lena Spetz; Jenny Hallgren Martinsson; Stockholms universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; single-stranded oligonucleotides; Toll-like receptors; influenza; respiratory syncytial virus; dendritic cell; mast cell; virus infection; inflammation; itch; molekylär biovetenskap; Molecular Bioscience;

    Sammanfattning : As the first line of defense, the innate immune system is exceptionally efficacious against invading pathogens but must be tightly regulated to avoid immune-related pathogenesis. Accordingly, the innate immune system recognizes highly conserved components associated with infections and damaged cells using a limited number of pattern-recognition receptors (PRRs), which are differentially expressed across cell types. LÄS MER

  4. 3. New Aspects of Mast Cell Progenitors in Health and Disease

    Författare :Maya Salomonsson; Jenny Hallgren Martinsson; Silvia Bulfone-Paus; Uppsala universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Mast cells; Mast cell progenitor; Lung function; Bone marrow; Blood; Activation; Chemotactic receptors;

    Sammanfattning : Mast cells are tissue-resident immune cells that are well known for their involvement in asthma and allergy. They originate in the fetal yolk sac, or in the bone marrow. From the bone marrow, they are released as immature progenitors that are transported via the blood circulation to the peripheral tissue, where they mature. LÄS MER