Sökning: "toll-like receptor 4"

Visar resultat 6 - 10 av 52 avhandlingar innehållade orden toll-like receptor 4.

1. 6. Early-life gut microbiota and breast milk oligosaccharides in relation to childhood immune maturation and allergy

   Författare :Ylva Margareta Sjögren; Eva Sverremark-Ekström; Outi Vaarala; Stockholms universitet; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; allergy; infant; gut microbiota; human milk oligosaccharides; Bifidobacterium; Lactobacillus; Bacteroides fragilis; Clostridium difficile; family size; secretory IgA; toll like receptor; Immunology; Immunologi; immunologi; Immunology;

   Sammanfattning : Atopic allergy is the most common chronic disease among children in the developed world. This high prevalence could be associated with low microbial exposure. The early gut microbiota appears to be important for immune maturation. LÄS MER

3. 7. Microbial and maternal influences on allergic sensitization during childhood: defining a role for monocytes

   Författare :Shanie Saghafian Hedengren; Eva Sverremark-Ekström; Susan Prescott; Stockholms universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Monocytes; allergic sensitization; maternal allergy; Toll-like receptor; p38-MAPK; IL-6; Epstein-Barr virus; early-life microbial exposure; NK cells; IFN-γ; Immunology; Immunologi; immunologi; Immunology;

   Sammanfattning : Allergic diseases are influenced by genetics and the environment. Maternal allergy appears to confer a higher risk for allergic sensitization than paternal allergy, suggesting an in utero influence. LÄS MER

4. 8. Role of toll-like receptors in host responses to mucosal bacterial infections

   Författare :Fredrik Bäckhed; Karolinska Institutet; Karolinska Institutet; []
   Nyckelord :;

   Sammanfattning : The first contact between invading bacteria and the host occurs at the mucosal surface. Interestingly, the mucosal linings of different organs are exposed to bacteria to various degrees. LÄS MER

5. 9. Cytokines and lipids in pregnancy – effects on developmental programming and placental nutrient transfer

   Författare :Susanne Lager; Göteborgs universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; adipose tissue; amino acids; cytokines; developmental programming; free fatty acids; insulin resistance; interleukin-6; lipoprotein lipase; nutrient transport; placenta; toll-like receptor 4;

   Sammanfattning : Metabolic disturbances, in particular those associated with nutritional challenges, that take place during development, both in utero and early postnatal life, have long-lasting health consequences on an individual. The most pronounced evidence of these challenges is a deviation in birth weight. LÄS MER

7. 10. Influence of host genetics on innate immunity and susceptibility to urinary tract infection

   Författare :Bryndis Ragnarsdottir; immunologi och glykobiologi - MIG Avdelningen för mikrobiologi; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; neutrophils; IRF3; Innate Immunity; urinary tract infections; acute pyelonephritis; asymptomatic bacteriuria; Toll-like receptor 4; CXCR1; TLR4 adaptors; polymorphisms;

   Sammanfattning : It has been known for a long time that the clinical manifestations of urinary tract infections (UTI) differ markedly between individuals, ranging from a sometimes beneficial, asymptomatic state to life threatening infections. This variability in clinical manifestation can be explained in part by the arsenal of virulence factors of the bacteria but the predisposition of the patient is equally important. LÄS MER