Sökning: "Tolllike receptors"

Hittade 5 avhandlingar innehållade orden Tolllike receptors.

  1. 1. Platelets in inflammation : Role of complement protein C1q, C-reactive proteinand toll-like receptors

    Författare :Caroline Skoglund; Torbjörn Bengtsson; Jonas Wetterö; Pentti Tengvall; David Erlinge; Linköpings universitet; []
    Nyckelord :MEDICINE; MEDICIN;

    Sammanfattning : Platelets are proven essential in haemostasis, however, they are now also increasingly recognized as cells with important immunomodulatory properties, e.g. through interaction with leukocytes and several species of bacteria and by release inflammatory mediators upon activation. LÄS MER

  2. 2. Preterm and term cervival ripening : Studies on CRH, HMGB1, toll-like receptors, cytokines and matrix metalloproteinases

    Författare :Aurelija Dubicke; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; Cervical fibroblasts; cervical ripening; cervix; chemokines; cytokines; CRH; HMGB1; interleukin; labor; preterm; preterm labor; matrix metalloproteinases; pregnancy; PPROM; Tolllike receptors;

    Sammanfattning : Objective: Preterm birth (PTB) is the leading cause of neonatal mortality and morbidity. Despite the existing treatment, the frequency of PTB has not changed in the past thirty years. Incomplete understanding of the biological and pathophysiological mechanisms underlying preterm delivery is the major obstacle to preventing PTB. LÄS MER

  3. 3. Bridging innate and adaptive immunity in cardiovascular disease

    Författare :Glykeria Karadimou; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP;

    Sammanfattning : Cardiovascular disease is the leading cause of death and morbidity in the world. Myocardial infarction and stroke constitute the main manifestations of atherosclerosis that lead to the majority of cardiovascular events. Calcific aortic valve stenosis is the most common valve pathology. LÄS MER

  4. 4. Glycan-based interactions of Streptococcus pneumoniae and the host

    Författare :Karina Hentrich; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP;

    Sammanfattning : Streptococcus pneumoniae is commonly found as an asymptomatic colonizer of the nasopharynx of children, but it can also translocate to normally sterile body sites and cause severe diseases, like pneumonia, septicemia or meningitis. Pneumococci spread via aerosols. LÄS MER

  5. 5. Studies on immunological mechanisms of induced arthritis in the rat

    Författare :Lena Svelander; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; Arthritis; autoimmunity; adjuvant; incomplete Freund s adjuvant; squalene; CpG;

    Sammanfattning : Experimental arthritis induced with adjuvants shares many features with the human autoimmune disorder rheumatoid arthritis (RA). The use of arthritis models is therefore a relevant approach in the search for pathogenic mechanisms in human disease. LÄS MER