Sökning: "Infection Resistance"

Visar resultat 1 - 5 av 377 avhandlingar innehållade orden Infection Resistance.

  1. 1. Epidemiology of Enterococci with Acquired Resistance to Antibiotics in Sweden : Special emphasis on Ampicillin and Vancomycin

    Författare :Erik Torell; Mats Kallin; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Communicable diseases; Antimicrobial resistance; enterococci; epidemiology in Sweden; intra-hospital spread; shedding; risk-factors; infection; colonization; virulence factors; ARE; VRE; Php; PFGE; esp; gyrA; parC; Infektionssjukdomar; Infectious diseases; Infektionssjukdomar; infektionssjukdomar; Infectious Diseases;

    Sammanfattning : The first hospital outbreak of vancomycin-resistant enterococci (VRE) and carriage rates of VRE and ampicillin-resistant enterococci (ARE) in Sweden were investigated. Clonal relationships and mutations in fluoroquinolone resistance determining regions among ARE collected nation-wide were studied. LÄS MER

  3. 2. Go with your gut : The human intestinal microbiota, international travel, Campylobacter and ESBL-producing Enterobacteriaceae

    Författare :Christian Kampmann; Hilpi Rautelin; Johan Dicksved; Lars Engstrand; Johan Tham; Johan Ursing; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; travel; travellers´diarrhea; microbiota; Campylobacter; Campylobacter jejuni; ST353CC; colonization resistance; enteritis; infection; Enterobacteriaceae; Christensenellaceae; Lachnospiraceae; whole genome sequence; vegetarian; bacterial resistance; ESBL; Extended spectrum beta-lactamase; probiotics; intestinal decolonization; eradication treatment; Infektionssjukdomar; Infectious Diseases;

    Sammanfattning : Up to 100 million people travel annually from industrialized countries to resource-limited ones. Each traveller contains an internal ecosystem composed of tens of trillions of microbes, known as the intestinal microbiota, which has a large effect on health. LÄS MER

  4. 3. Antimicrobial peptides in the treatment of infectious and inflammatory conditions : Preclinical studies of mechanism of action, efficacy, and safety

    Författare :Camilla Björn; RISE; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; antimicrobial peptides; AMPs; innate immunity; infection; inflammation; mechanism of action; efficacy; safety; antimicrobial resistance; antibiotic resistance; Antimicrobial peptides; AMPs; innate immunity; infection; inflammation; mechanism of action; efficacy; safety; antimicrobial resistance; antibiotic resistance;

    Sammanfattning : The rapid emergence of antibiotic-resistant microbes worldwide and the urgent need of new antimicrobial agents have stimulated interest in antimicrobial peptides (AMPs) as new therapeutics for treatment of infectious diseases. AMPs are present in all living species and constitute an important part of the innate immune system in multicellular organisms, including humans. LÄS MER

  5. 4. Mutations and Mutation Rate in the Development of Fluoroquinolone Resistance

    Författare :Patricia Komp Lindgren; Diarmaid Hughes; Fernando Baquero; Uppsala universitet; []
    Nyckelord :Microbiology; Mutation rate; Fluoroquinolone; Resistance; Biological fitness; Urinary tract infection; Escherichia coli; MPC; Mikrobiologi;

    Sammanfattning : The emergence of multidrug resistant bacteria world wide is a serious problem, and very few new drugs are under development. The selection of resistant bacteria is affected by factors such as mutation rate, biological fitness cost and the rate of fitness compensation. LÄS MER

  7. 5. Resistance to Fluoroquinolones in Escherichia coli: Prevention, Genetics and Fitness Costs

    Författare :Linda L. Marcusson; Diarmaid Hughes; Karl Drlica; Uppsala universitet; []
    Nyckelord :Biology; Fluoroquinolone; Escherichia coli; Resistance; Gyrase; Topoisomerase IV; MPC; Fitness compensation; Urinary Tract Infection; Biologi;

    Sammanfattning : Antibiotic-resistant bacteria are increasingly a major healthcare problem but very few new classes of antibiotics have been discovered or launched in recent decades. Approaches to dealing with the problem include learning how bacteria evolve to resistance and improving dosing regimens with current antibiotics so as to reduce the selection of resistant bacteria. LÄS MER