Sökning: "skeletal site"

Visar resultat 41 - 45 av 55 avhandlingar innehållade orden skeletal site.

  1. 41. Predictors of bone fragility in older women. Associations in older women between risk medications and measurements of physical function, bone microstructure and fracture risk

    Författare :Berit A M Larsson; Göteborgs universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; osteoporosis; risk prediction; fracture; risk medication; selective serotonin reuptake inhibitors; statins; physical function; timed up and go; one leg standing test;

    Sammanfattning : Bone fragility with fractures constitutes a growing public health concern, resulting in suffering and major health care cost. This thesis project has been carried out by means of studies based on the SUPERB cohort of 75–80-year-old women from Gothenburg. LÄS MER

  3. 42. Integrating multi-omics for type 2 diabetes : Data science and big data towards personalized medicine

    Författare :Klev Diamanti; Jan Komorowski; Claes Wadelius; Manfred Grabherr; Peter Spégel; Uppsala universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; type 2 diabetes; multi-omics; genomics; metabolomics; data science; machine learning; personalized medicine; Bioinformatics; Bioinformatik;

    Sammanfattning : Type 2 diabetes (T2D) is a complex metabolic disease characterized by multi-tissue insulin resistance and failure of the pancreatic β-cells to secrete sufficient amounts of insulin. Cells recruit transcription factors (TF) to specific genomic loci to regulate gene expression that consequently affects the protein and metabolite abundancies. LÄS MER

  4. 43. Studies on novel interactors in human adipose tissue

    Författare :Amanda T Pettersson; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Obesity is associated with a mild inflammation and altered protein secretion in adipose tissue. These changes have been suggested to contribute to the development of obesity-associated disorders including, insulin resistance, dyslipidemia, type 2 diabetes and cardiovascular disease. LÄS MER

  5. 44. Finger Joint Reconstruction with Rib Perichondrium

    Författare :Daniel Muder; Torbjörn Vedung; Nils Hailer; Ola Nilsson; Simon Farnebo; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; finger joint; reconstruction; cartilage; transplantation; osteoarthritis; Orthopaedics; Ortopedi;

    Sammanfattning : Difficulties in repairing and reconstructing articular cartilage damaged by trauma or disease remain unsolved and are one of the major challenges confronting orthopedic and hand surgeons in their clinical work. Relevant research has not adequately described the long-term clinical results, nor has it made a direct comparison to implant surgery after finger joint reconstruction with rib perichondrium. LÄS MER

  7. 45. Molecular Palaeopathology : Ancient DNA analyses of the bacterial diseases tuberculosis and leprosy

    Författare :Emilia Nuorala; Kerstin Lidén; Ingrid Ekenman; Marie Allen; Stockholms universitet; []
    Nyckelord :HUMANIORA; HUMANITIES; molecular palaeopathology; ancient DNA; disease; bacteria; tuberculosis; leprosy; Archaeology subjects; Arkeologiämnen;

    Sammanfattning : This thesis “Molecular Palaeopathology. Ancient DNA analyses of the bacterial diseases tuberculosis and leprosy” deals with molecular palaeopathology, i.e. in this case the use of molecular methods to analyse ancient bacterial DNA in order to get further knowledge of diseases in ancient times. LÄS MER