Sökning: "polycyclic aromatic hydrocarbon"

Visar resultat 6 - 10 av 23 avhandlingar innehållade orden polycyclic aromatic hydrocarbon.

  1. 6. Selective Retention of β-Carbolines and 7,12-Dimethylbenz[a]anthracene in the Brain : Role of Neuromelanin and Cytochrome P450 for Toxicity

    Författare :Anna Östergren; Eva Brittebo; Nils Gunnar Lindquist; Anne-Lie Svensson; Hans Tjälve; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Toxicology; β-carboline; neuromelanin; norharman; harman; parkinsonism; Parkinson s disease; motoric impairment; behaviour; glia cells; substantia nigra; dopamine melanin; PC12 cells; ER stress; grp78; hsp90; cytochrome P450; CYP1A1; CYP1B1; blood-brain interfaces; 7; 12-dimethylbenz[a]anthracene; polycyclic aromatic hydrocarbon; endothelial cell; smooth muscle cell; bioactivation; Toxikologi; Toxicology; Toxikologi; Toxicology; toxikologi;

    Sammanfattning : The ß-carbolines norharman and harman structurally resemble the synthetic compound 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) that is known for its ability to damage neuromelanin-containing dopaminergic neurons of the substantia nigra and thereby induce parkinsonism. MPTP is, however, not normally present in the environment whereas the ß-carbolines are present in cooked food and tobacco smoke. LÄS MER

  3. 7. Automation, hyphenation and multidimensional chromatography for PAH analysis : Analytical techniques to simplify sample complexity

    Författare :Hwanmi Lim; Roger Westerholm; Christoffer Bergvall; Stephen Wise; Stockholms universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; polycyclic aromatic hydrocarbon; PAH; benzo[a]pyrene; B[a]P; carcinogenicity; cancer risk assessment; complex matrix; automation; hyphenation; multidimensional chromatography; two-dimensional; method translation; online fractionation; benz[j]aceanthrylene; B[j]A; relative potency factor; Analytical Chemistry; analytisk kemi;

    Sammanfattning : One group of organic environmental pollutants which are potentially hazardous to human health is polycyclic aromatic hydrocarbons (PAHs). These compounds consist of two or more benzene rings in their structure among which benzo[a]pyrene (B[a]P) is classified as a human carcinogen. LÄS MER

  4. 8. Properties and hormonal regulation of polycyclic aromatic hydrocarbon metabolism by the cytochrome P-450 system in the mammalian ovary

    Författare :Margot Bengtsson; Stockholms universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES;

    Sammanfattning : .... LÄS MER

  5. 9. From source to the environment : Strategies for identification and determination of hydroxylated polycyclic aromatic hydrocarbons in complex particulate matrices

    Författare :Rozanna Avagyan; Roger Westerholm; Conny Östman; Marja-Liisa Riekkola; Stockholms universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; OH-PAHs; hydroxy-PAHs; particulate matter; PM; airborne particles; combustion particles; wood combustion; suspect screening; non-target screening; high resolution mass spectrometry; HRMS; atmospheric pressure photoionization; APPI; Analytical Chemistry; analytisk kemi;

    Sammanfattning : Adverse health effects have been linked to exposure to particulate matter, and wood combustion is considered as an important source of harmful particulate matter in the urban air and environment. Hydroxylated polycyclic aromatic hydrocarbons are a group of compounds with toxic, endocrine disrupting and carcinogenic properties. LÄS MER

  7. 10. Biodegradation of hydrocarbons in soil and water

    Författare :Mikael Eriksson; KTH; []
    Nyckelord :Solid Phase Microextraction; SPME; biodegradation; bioremediation; bioavailability; monitoring; Volatile Organic Compounds VOC ; Screening; headspace sampling; polycyclic aromatic hydrocarbons; PAHs; aliphatic hydrocarbons; total petroleum hydrocarb;

    Sammanfattning : Biodegradation of aliphatic and polycyclic aromatichydrocarbons was studied in soil and liquid cultures attemperatures ranging from -5 º C to 20 º C undervarious aerobic or anaerobic, nitrate reducing, conditions. Twocontaminated soils were used in the studies. LÄS MER