Sökning: "high resolution mass spectrometry"
Visar resultat 1 - 5 av 130 avhandlingar innehållade orden high resolution mass spectrometry.
1. Novel strategies to increase throughput and differentiate lipid isomers in mass spectrometry imaging : Development of computational tools and complex mass spectrometric methods for nanospray desorption electrospray ionization
Sammanfattning : In this thesis, method development for improved analyte identification and throughput in mass spectrometry imaging (MSI) is discussed. In MSI, the spatial distribution of analytes from a sample is determined and visualized, information about the detected molecules interaction within the sample can thereby the deduced. LÄS MER
2. Analytical developments and applications of ambient mass spectrometry imaging : Visualizing challenging analytes and understanding chemical mechanisms of ischemic stroke
Sammanfattning : Bioanalytical methods that provide spatial information on molecular distributions are important for deep understanding of chemical mechanisms in health and disease. For instance, the localized action of drugs and metabolites can provide valuable information on metabolism in specific cellular regions, which would not be possible with bulk analysis. LÄS MER
3. New Materials and Improved Ambient Techniques in Mass Spectrometry
Sammanfattning : Mass spectrometry (MS) is used in several fields, e.g. biology, environmental monitoring, medicine and forensics due to excellent qualitative and quantitative capabilities. The development of new instrumental setups and ionization sources is crucial to analyze a variety of compounds at trace levels. LÄS MER
4. Mass Spectrometry of Biologically Active Small Molecules : Focusing on polyphenols, alkaloids and amino acids
Sammanfattning : The foci of this dissertation are on advanced liquid chromatography (LC) separation and mass spectrometry (MS) techniques for the analysis of small bioactive molecules. In addition to discussing general aspects of such techniques the results from analyses of polyphenols (PPs), alkaloids and amino acids published in five appended studies are presented and discussed. LÄS MER
5. Characterisation of natural dissolved organic matter with liquid chromatography and high resolution mass spectrometry
Sammanfattning : Dissolved organic matter (DOM) is one of the most heterogeneous and complex mixture on Earth. DOM plays a crucial role in biogeochemical processes on the global scale and it is essential to sustain and regulate the biological processes in aquatic ecosystems. LÄS MER