Sökning: "high resolution mass spectrometry"

Visar resultat 1 - 5 av 92 avhandlingar innehållade orden high resolution mass spectrometry.

  1. 1. New Materials and Improved Ambient Techniques in Mass Spectrometry

    Detta är en avhandling från Stockholm : Department of Environmental Science and Analytical Chemistry, Stockholm University

    Författare :Nicolò Riboni; Stockholms universitet.; [2019]
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Mass Spectrometry; Solid Phase Microextraction; Ambient Mass Spectrometry; Desorption Electrospray Ionization; Paper Spray Ionization; Cavitands; BTEX; New Psychoactive Substances; Analytical Chemistry; analytisk kemi;

    Sammanfattning : Mass spectrometry (MS) is used in several fields, e.g. biology, environmental monitoring, medicine and forensics due to excellent qualitative and quantitative capabilities. The development of new instrumental setups and ionization sources is crucial to analyze a variety of compounds at trace levels. LÄS MER

  2. 2. Mass Spectrometry of Biologically Active Small Molecules Focusing on polyphenols, alkaloids and amino acids

    Detta är en avhandling från Stockholm : Department of Analytic Chemistry, Stockholm University

    Författare :Zdeněk Spáčil; Stockholms universitet.; [2010]
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; LC-MS; LDI; Mass spectrometry; HPLC; UHPLC; polyphenols; phenolic acids; BMAA; NATURAL SCIENCES Chemistry Analytical chemistry Separation methods; NATURVETENSKAP Kemi Analytisk kemi Separationsmetoder; NATURAL SCIENCES Chemistry Analytical chemistry; NATURVETENSKAP Kemi Analytisk kemi; Analytical Chemistry; analytisk kemi;

    Sammanfattning : The foci of this dissertation are on advanced liquid chromatography (LC) separation and mass spectrometry (MS) techniques for the analysis of small bioactive molecules. In addition to discussing general aspects of such techniques the results from analyses of polyphenols (PPs), alkaloids and amino acids published in five appended studies are presented and discussed. LÄS MER

  3. 3. Bioanalysis using capillary electrophoresis and mass spectrometry Applied on proteins, protein nanofibrils and polyvinyl alcohol microbubbles

    Detta är en avhandling från Stockholm : KTH Royal Institute of Technology

    Författare :Leila Josefsson; KTH.; [2019]
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; : amyloid; capillary electrophoresis; contrast agents; detection; human blood plasma; ionic liquids; mass spectrometry; microbubbles; polyvinyl alcohol microbubbles; protein nanofibrils; proteins; Kemi; Chemistry;

    Sammanfattning : The sequencing of the genome of various species, including the human species, have led to increased understanding about how a protein structure is generated, and how specific structures are related to the proteins’ functionality. In paper I and II of this thesis, the folding of proteins in vitro to form hierarchical nanostructures, which in vivo often have a pathological effect, have been studied. LÄS MER

  4. 4. Advanced Mass Spectrometry Imaging in Neuropharmacology

    Detta är en avhandling från Uppsala : Acta Universitatis Upsaliensis

    Författare :Theodosia Vallianatou; Uppsala universitet.; [2019]
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; mass spectrometry imaging; neuropharmacology; blood brain barrier; drug-drug interactions; aging; tacrine;

    Sammanfattning : Mass spectrometry imaging (MSI) has emerged as a valuable approach for mapping multiple molecular species in sections of diverse tissues. It enables simultaneous detection of numerous compounds (from neurotransmitters to small proteins) in the brain at relatively high lateral resolution (>5 μm) on a routine basis. LÄS MER

  5. 5. Molecular and epidemiological studies on eyes with pseudoexfoliation syndrome

    Detta är en avhandling från Uppsala : Acta Universitatis Upsaliensis

    Författare :Amelie Botling Taube; Uppsala universitet.; [2015]
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Pseduoexfoliation syndrome; PEX; aqueous humor; cataract; cataract surgery; lens capsule; proteomics; mass spectrometry; MS; MALDI TOF MS MS; quantitative proteomics; iTRAQ; dimethyl labeling; imaging mass spectrometry; IMS; time of flight secondary ion mass spectrometry; TOF-SIMS; crystallin; epidemiology; risk factor; Ophtalmology; Oftalmiatrik;

    Sammanfattning : Pseudoexfoliation (PEX) syndrome is an age-related condition characterized by the production and accumulation of extracellular fibrillary material in the anterior segment of the eye. PEX predisposes for several pathological conditions, such as glaucoma and complications during and after cataract surgery. LÄS MER