Sökning: "morphine"

Visar resultat 1 - 5 av 118 avhandlingar innehållade ordet morphine.

  1. 1. Morphine and pregnancy : aspects of the use of morphine and morphine-related compounds

    Författare :Eva Gerdin; Uppsala universitet; []
    Nyckelord :MEDICINE; MEDICIN;

    Sammanfattning : .... LÄS MER

  3. 2. The incurable cancer patient at the end of life : Medical care utilization, quality of life and the additive analgesic effect of paracetamol in concurrent morphine therapy

    Författare :Bertil Axelsson; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Surgery; Palliative; cancer; place of death; health care utilization; quality of life; morphine; paracetamol; pain; Kirurgi; Surgery; Kirurgi; Surgery; kirurgi;

    Sammanfattning : Only 12% of the patients died at home. When the period between diagnosis and death was less than one month, every patient died in an institution. Younger patients, marriedpatients, and those living within the 40 km radius of the hospital utilized more hospital days. LÄS MER

  4. 3. Spinal morphine and pethidine : pharmacokinetics and patient-controlled analgesia

    Författare :Staffan Sjöström; Uppsala universitet; []
    Nyckelord :MEDICINE; MEDICIN;

    Sammanfattning : .... LÄS MER

  5. 4. Microdialysis and Intensive Care. Clinical and experimental studies

    Författare :Per Ederoth; Anestesiologi och intensivvård; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Anaesthesiology; traumatic brain injury; glucose; glycerol; lipolysis; epidural; postoperative analgesia; experimental pancreatitis; human; blood-brain barrier; morphine; pharmacokinetics; Microdialysis; intensive care; Anestesiologi; intensivvård;

    Sammanfattning : Microdialysis was used to monitor local concentrations of energy metabolites in different organs, and to study the pharmacokinetics of morphine over the blood-brain barrier in intact and injured brain tissue in conditions treated in the Intensive Care Unit. After major abdominal or thoracoabdominal surgery, postoperative thoracic epidural analgesia resulted in higher glycerol concentrations in the deltoid subcutaneous adipose tissue, implying increased lipolysis, on the third postoperative day as compared to intravenous infusion of morphine, possibly due to a locally increased sympathetic tone. LÄS MER

  7. 5. Developmental Aspects of Drug Transport Across the Blood-Brain Barrier

    Författare :Jörgen Bengtsson; Margareta Hammarlund-Udenaes; Ann-Cathrin Engwall; Sven Björkman; Elizabeth C.M. de Lange; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Blood-brain barrier; development; active transport; tight junction proteins; microdialysis; recovery; morphine; nitrofurantoin; Bcrp; microarray; real-time PCR; in vitro; in vivo; LC-MS MS; Biopharmacy; Biofarmaci; Pharmacokinetics and Drug Therapy; Farmakokinetik och läkemedelsterapi;

    Sammanfattning : The developmental aspect of drug transport across the blood-brain barrier (BBB) was investigated. Microdialysis was used to study unbound morphine BBB transport at different ages in sheep. An in vitro study was performed to find differentially expressed genes in brain capillary-rich fractions of the brain in rats of different ages. LÄS MER