Sökning: "Eva Brittebo"
Visar resultat 1 - 5 av 9 avhandlingar innehållade orden Eva Brittebo.
1. Distribution and metabolism of some N-nitroso compounds : N-dimethylnitrosamine, N-nitrosopyrrolidine, N1-nitrosonornicotine, streptozotocin and N-ethyl-N-nitrosourea
Sammanfattning : .... LÄS MER
2. Experimental Studies of Endocrine Disrupting Compounds in Vascular Cells and Tissues
Sammanfattning : Epidemiological evidence suggest that exposure to endocrine disrupting compounds (EDCs) is a risk factor for diseases that involves the cardiovascular system but we know little about the mechanisms whereby these compounds can cause injury in the vasculature. The aim of this thesis was to characterize the effects and mechanisms of some EDCs in vascular cells and highly vascularized tissues. LÄS MER
3. β-N-methylamino-L-alanine (BMAA)-induced neurotoxicity : Studies in vitro and in vivo
Sammanfattning : β-N-methylamino-L-alanine (BMAA) is a neurotoxic non-proteinogenic amino acid produced naturally by cyanobacteria, diatoms and dinoflagellates and it has been detected in samples from fresh and marine water from all over the world. It can bioaccumulate in fish and shellfish, and has a potential to biomagnify in a terrestrial food chain. LÄS MER
4. Olfactory Transfer of Analgesic Drugs After Nasal Administration
Sammanfattning : Nasal administration of analgesics for achieving rapid pain relief is currently a topic of great interest. The blood-brain barrier (BBB) restricts access to the central nervous system (CNS) for several central-acting drugs, such as morphine and dihydroergotamine, which results in a substantial effect delay. LÄS MER
5. Tissue-Selective Activation and Toxicity of Substituted Dichlorobenzenes : Studies on the Mechanism of Cell Death in the Olfactory Mucosa
Sammanfattning : The nasal passages are constantly exposed to both air- and bloodborne foreign compounds. In particular, the olfactory mucosa is demonstrated to be susceptible to a variety of drugs and chemicals. LÄS MER