Sökning: "Anna Östergren"

Hittade 3 avhandlingar innehållade orden Anna Östergren.

  1. 1. Selective Retention of β-Carbolines and 7,12-Dimethylbenz[a]anthracene in the Brain : Role of Neuromelanin and Cytochrome P450 for Toxicity

    Författare :Anna Östergren; Eva Brittebo; Nils Gunnar Lindquist; Anne-Lie Svensson; Hans Tjälve; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Toxicology; β-carboline; neuromelanin; norharman; harman; parkinsonism; Parkinson s disease; motoric impairment; behaviour; glia cells; substantia nigra; dopamine melanin; PC12 cells; ER stress; grp78; hsp90; cytochrome P450; CYP1A1; CYP1B1; blood-brain interfaces; 7; 12-dimethylbenz[a]anthracene; polycyclic aromatic hydrocarbon; endothelial cell; smooth muscle cell; bioactivation; Toxikologi; Toxicology; Toxikologi; Toxicology; toxikologi;

    Sammanfattning : The ß-carbolines norharman and harman structurally resemble the synthetic compound 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) that is known for its ability to damage neuromelanin-containing dopaminergic neurons of the substantia nigra and thereby induce parkinsonism. MPTP is, however, not normally present in the environment whereas the ß-carbolines are present in cooked food and tobacco smoke. LÄS MER

  2. 2. Yesterday once more? Unemployment and health inequalities across the life course in northern Sweden

    Författare :Anna Brydsten; Miguel San Sebastian; Anne Hammarström; Mattias Strandh; Per-Olof Östergren; Umeå universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; unemployment; life course; long-term health consequences; health inequity; national unemployment rates; neighbourhood unemployment rates; northern Sweden; arbetslöshet; livslopp; långsiktiga hälsokonsekvenser; ojämlikhet i hälsa; nationella arbetslöshet; arbetslöshet i bostadsområdet; norra Sverige; folkhälsa; Public health; Epidemiology; epidemiologi; socialmedicin; Social Medicine;

    Sammanfattning : AbstractBackground. It is relatively well established in previous research that unemployment has direct health consequences in terms of mental and physical ill health. Recently, knowledge has emerged indicating that unemployment can lead to economic consequences that remain long after re-establishment in the labour market. LÄS MER

  3. 3. Patient safety at emergency departments : challenges with crowding, multitasking and interruptions

    Författare :Lena M Berg; Katarina Göransson; Anna Ehrenberg; Jan Florin; Jan Östergren; Birgitta Wireklint Sundström; Karolinska Institutet Solna Department of Medicine; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES;

    Sammanfattning : Several challenges with patient safety in the emergency department (ED) context have beenpreviously identified, and some commonly mentioned are crowding, multitasking, andinterruptions. The ED is a complex, high-risk work environment where multiple clinicians(physicians, registered nurses [RNs], and licensed practical nurses [LPNs]) are constantlyworking in parallel work processes, in an often crowded ED, while conducting tasksinvolving cognitively demanding decision-making processes. LÄS MER