Sökning: "B[a]P"

Visar resultat 1 - 5 av 6 avhandlingar innehållade ordet B[a]P.

  1. 1. Automation, hyphenation and multidimensional chromatography for PAH analysis : Analytical techniques to simplify sample complexity

    Författare :Hwanmi Lim; Roger Westerholm; Christoffer Bergvall; Stephen Wise; Stockholms universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; polycyclic aromatic hydrocarbon; PAH; benzo[a]pyrene; B[a]P; carcinogenicity; cancer risk assessment; complex matrix; automation; hyphenation; multidimensional chromatography; two-dimensional; method translation; online fractionation; benz[j]aceanthrylene; B[j]A; relative potency factor; Analytical Chemistry; analytisk kemi;

    Sammanfattning : One group of organic environmental pollutants which are potentially hazardous to human health is polycyclic aromatic hydrocarbons (PAHs). These compounds consist of two or more benzene rings in their structure among which benzo[a]pyrene (B[a]P) is classified as a human carcinogen. LÄS MER

  3. 2. Molecular and phenotypical toxicological effects of environmental pollutants and their mixtures : A mechanistic approach

    Författare :Greta Nilén; Steffen Keiter; Maria Larsson; Nikolai Scherbak; Magnus Engwall; Malin Celander; Örebro universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Environmental pollutants; mixtures; soil; zebrafish; Danio rerio; behavior; gene expression; lipidomics; image analysis; PCB126; PFOS; B[a]P; Arsenic; risk assessment;

    Sammanfattning : Current environmental risk assessment of polluted sites primarily relies on single compound evaluation. However, in the environment, organisms are often exposed to complex mixtures of pollutants. LÄS MER

  4. 3. Methods for Determination of Benzo(a)pyrene and High Molecular Weight (>300 Da) Polycyclic Aromatic Hydrocarbons in Particulate Matter from Ambient Air and Vehicle Exhausts

    Författare :Christoffer Bergvall; Roger Westerholm; Stephen Wise; Stockholms universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; PAH; dibenzopyrene; benzo a pyrene; standard reference material; air particulate matter; diesel particulate matter; toxic equivalence factor; ultrasonic assisted extraction; accelerated solvent extraction; automation; online coupling; GC MC; LC GC MS; Analytical chemistry; Analytisk kemi; Analytical Chemistry; analytisk kemi;

    Sammanfattning : Air pollution with particulate matter (PM) raises considerable concern because of its adverse effects on human health. For this reason, and because the mechanisms of PM toxicity are not fully known, there is an urgent need to determine the chemical constituents of atmospheric PM, especially PM emanating from traffic - a major source of urban PM. LÄS MER

  5. 4. Bioactivation and binding of polycyclic aromatic hydrocarbons in blood vessel endothelia

    Författare :Lizette Granberg; Uppsala universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Developmental biology; Polycyclic aromatic hydrocarbon; PAH; endothelial cells; Utvecklingsbiologi; Developmental biology; Utvecklingsbiologi; Ecotoxicology; ekotoxikologi;

    Sammanfattning : Polycyclic aromatic hydrocarbons (PAHs) are widespread environmental pollutants formed by incomplete combustion of organic materials such as fossil fuels and wood. Experimental and epidemiological studies indicate that PAHs may be involved in the development of cardiovascular disease. LÄS MER

  7. 5. Mutagenesis induced by xenobiotics : factors of importance and modification, with special emphasis on glutathione and glutathione transferases

    Författare :Lennart Romert; Stockholms universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Genetics; genetik;

    Sammanfattning : Genetic changes induced by chemical agents can result in cancer. Such tumor formation can be linked to activationof oncogenes, often through specific, definable mutagenic events, e.g., single base-pair mutation in specific codons. LÄS MER