Sökning: "myosin"

Visar resultat 16 - 20 av 113 avhandlingar innehållade ordet myosin.

  1. 16. Function of contractile and cytoskeletal proteins in smooth muscle: Effects of hypertrophy and age and desmin removal in a transgenic animal

    Författare :Rolf Sjuve; Institutionen för experimentell medicinsk vetenskap; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; transgenic mouse; desmin; embryonic myosin; isoforms; myosin heavy chain; age; smooth muscle; hypertrophy; Physiology; Fysiologi;

    Sammanfattning : In man, the urinary bladder responds to an urinary outflow obstruction with a pronounced dilatation and growth of the bladder wall. This clinical situation can be mimicked in rat by creation of a partial urinary outflow obstruction and the papers included in the present thesis use this animal model to address questions regarding the adaptive changes in the smooth muscle of the growing bladder. LÄS MER

  2. 17. Outcomes of Myosin 1C Gene Expression Depletion on Cancer-related Pathways, in Vitro and in Clinical Samples

    Författare :Anna Pfister; Afrouz Behboudi; Sahlgrenska Academy at University of Gothenburg; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MYO1C; myosin 1C; gene expression; pathway analysis; endometrial carcinoma;

    Sammanfattning : The unconventional myosin IC has previously been suggested to be a haploinsufficient tumour suppressor. The mechanism for this action has hitherto been unknown, however, and hence we decided to attempt to elucidate the genes involved. LÄS MER

  3. 18. Cellular and Molecular Mechanisms Underlying Acute Quadriplegic Myopathy : Studies in Experimental Animal Models and Intensive Care Unit Patients

    Författare :Holly Norman; Lars Larsson; Thomas Sejersen; Uppsala universitet; []
    Nyckelord :Neurosciences; Acute Quadriplegic Myopathy; intensive care unit; atrophy; myosin heavy chain; actin; myosin binding proteins; nuclear transcription factors; mRNA; Neurovetenskap;

    Sammanfattning : The combination of a severe systemic illness, corticosteroids, and neuromuscular blocking agents in patients on the mechanical ventilator often results in a condition known as Acute Quadriplegic Myopathy (AQM). While severe weakness of all spinal nerve innervated muscles is known to be a significant clinical characteristic of the disease, this symptom is typically not recognized until the disease has progressed to an advanced stage. LÄS MER

  4. 19. Cooperativity in muscle proteins : a study of actin filaments and myosin II

    Författare :Elina Bengtsson; Alf Månsson; Sven Tågerud; Ann-Christin Koch-Schmidt; Georgios Tsiavaliaris; Linnéuniversitetet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Cell and Organism Biology; Cell- och organismbiologi;

    Sammanfattning : .... LÄS MER

  5. 20. Actin and myosin in transcription and chromatin regulation

    Författare :Bader Almuzzaini; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : In mammalian cells, actin and myosin have emerged as regulators of nuclear structure and function, involved in chromatin remodeling and histone modifications, and in different phases of gene transcription. Actin and myosin have also been shown to be incorporated into nascent ribonucleoprotein complexes. LÄS MER