Sökning: "myosin 1C"
Hittade 3 avhandlingar innehållade orden myosin 1C.
1. Outcomes of Myosin 1C Gene Expression Depletion on Cancer-related Pathways, in Vitro and in Clinical Samples
Sammanfattning : The unconventional myosin IC has previously been suggested to be a haploinsufficient tumour suppressor. The mechanism for this action has hitherto been unknown, however, and hence we decided to attempt to elucidate the genes involved. LÄS MER
Sammanfattning : In mammalian cells, actin and myosin have emerged as regulators of nuclear structure and function, involved in chromatin remodeling and histone modifications, and in different phases of gene transcription. Actin and myosin have also been shown to be incorporated into nascent ribonucleoprotein complexes. LÄS MER
Sammanfattning : In the eukaryotic cell nucleus, actin and nuclear myosin 1c (NM1) are key regulators of RNA polymerase I (Pol I) transcription and function across the entire ribosomal RNA biogenesis pathway. At the gene level, actin interacts with Pol I and together with NM1 they have been suggested to facilitate assembly of Pol I at the gene promoter. LÄS MER