Sökning: "myosin 1C"

Hittade 4 avhandlingar innehållade orden myosin 1C.

  1. 1. Outcomes of Myosin 1C Gene Expression Depletion on Cancer-related Pathways, in Vitro and in Clinical Samples

    Författare :Anna Pfister; Afrouz Behboudi; Sahlgrenska Academy at University of Gothenburg; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MYO1C; myosin 1C; gene expression; pathway analysis; endometrial carcinoma;

    Sammanfattning : The unconventional myosin IC has previously been suggested to be a haploinsufficient tumour suppressor. The mechanism for this action has hitherto been unknown, however, and hence we decided to attempt to elucidate the genes involved. LÄS MER

  3. 2. Myosin 1c taking adrenergic metabolism for a spin : More than a motor protein

    Författare :Alice Åslund; Tore Bengtsson; Michael Czech; Stockholms universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Glucose uptake; Glucose transporter; Brown adipose tissue; White adipose tissue; Skeletal muscle; Myosin1c; Nuclear myosin I; Physiology; molekylär biovetenskap; Molecular Bioscience;

    Sammanfattning : Metabolic diseases like type II diabetes (T2D) and obesity largely stems from an unbalanced energy homeostasis with the fails of the insulin pathway to the point in which the glucose homeostasis is severely disturbed leading to hyperglycemia. We have investigated if the β-adrenergic signaling pathways, in both brown adipose tissue (BAT) and skeletal muscle, could be used as a strategy to alleviate metabolic disease. LÄS MER

  4. 3. Actin and myosin in transcription and chromatin regulation

    Författare :Bader Almuzzaini; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : In mammalian cells, actin and myosin have emerged as regulators of nuclear structure and function, involved in chromatin remodeling and histone modifications, and in different phases of gene transcription. Actin and myosin have also been shown to be incorporated into nascent ribonucleoprotein complexes. LÄS MER

  5. 4. Transcriptional regulation of ribosomal RNA gene : actin, myosin and beyond

    Författare :Aishe Angeletti Sarshad; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : In the eukaryotic cell nucleus, actin and nuclear myosin 1c (NM1) are key regulators of RNA polymerase I (Pol I) transcription and function across the entire ribosomal RNA biogenesis pathway. At the gene level, actin interacts with Pol I and together with NM1 they have been suggested to facilitate assembly of Pol I at the gene promoter. LÄS MER