Sökning: "myosin"

Visar resultat 6 - 10 av 113 avhandlingar innehållade ordet myosin.

  1. 6. Biophysical studies of the actin-myosin motor system and applications in nanoscience

    Författare :Mohammad A. Rahman; Alf Månsson; Kazuhiro Oiwa; Linnéuniversitetet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; myosin II; actin; actomyosin force generating cycle; blebbistatin; in vitro motility assay; actin affinity purification; blocking actin; bionanodevices; proteinase k; SDS; triton X100; surface recycling; engineered myosin motor; programmable gate; biocomputation.; Biomedical Sciences; Biomedicinsk vetenskap;

    Sammanfattning : The actin-myosin motor system plays important roles in cellular processes. In addition, actin and myosin have been used for developments towards nanotechnological applications in recent years. LÄS MER

  3. 7. Nanofabricated Devices Based on Molecular Motors: Biosensing, Computation and Detection

    Författare :Mercy Lard; Fasta tillståndets fysik; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; biocomputing; actin; hollow nanowires; molecular concentration; molecular motors; nano-biosensor; myosin; nano-fabrication; nanowires; Fysicumarkivet A:2014:Lard;

    Sammanfattning : The thesis describes the use of molecular motors in nanofabricated devices designed for potential applications in biosensing, computation and detection. We utilize the well-established guiding principles for controlling the motion of actin filaments propelled by myosin molecular motors, and build upon these developments in order to improve upon previously demonstrated techniques, and establish new methods that, we believe, offer significant progress in these fields. LÄS MER

  4. 8. Intensive Care Unit Muscle Wasting : Skeletal Muscle Phenotype and Underlying Molecular Mechanisms

    Författare :Sudhakar Reddy Aare; Larsson Lars; Rooyackers Olav; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; acute quadriplegic myopathy; gene expression; myosin; heat shock proteins; mechanical ventilation; myostatin; sepsis; corticosteroids; diaphragm; Clinical Neurophysiology; Klinisk neurofysiologi;

    Sammanfattning : Acute quadriplegic myopathy (AQM), or critical illness myopathy, is a common debilitating acquired disorder in critically ill intensive care unit (ICU) patients characterized by generalized muscle wasting and weakness of limb and trunk muscles. A preferential loss of the thick filament protein myosin is considered pathognomonic of this disorder, but the myosin loss is observed relatively late during the disease progression. LÄS MER

  5. 9. Human extraocular muscles : molecular diversity of a unique muscle allotype

    Författare :Daniel Kjellgren; Fatima Pedrosa-Domellöf; Lars-Erik Thornell; Lillemor Wachtmeister; John Porter; Umeå universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Ophtalmology; extraocular; muscle; myosin; protein c; laminin; serca; immunocytochemistry; human; Oftalmiatrik; Ophtalmology; Oftalmologi; oftalmiatrik; Ophtalmology;

    Sammanfattning : Introduction: The extraocular muscles (EOMs) are considered a separate class of skeletal muscle, allotype. Myosin is the major contractile protein in muscle. The myosin heavy chain (MyHC) isoforms are the best molecular markers of functional heterogeneity of muscle fibers. LÄS MER

  7. 10. Cellular and Molecular Mechanisms Underlying Congenital Myopathy-related Weakness

    Författare :Johan Lindqvist; Julien Ochala; Anders Arner; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; skeletal muscle; skeletal muscle contraction; atrophy; nemaline myopathy; myofibrillar myopathy; myosin; actin;

    Sammanfattning : Congenital myopathies are a rare and heterogeneous group of diseases. They are primarily characterised by skeletal muscle weakness and disease-specific pathological features. They harshly limit ordinary life and in severe cases, these myopathies are associated with early death of the affected individuals. LÄS MER