Sökning: "mitochondrial fission"

Visar resultat 1 - 5 av 13 avhandlingar innehållade orden mitochondrial fission.

  1. 1. Adaptive divergence in fission yeast : From experimental evolution to evolutionary genomics

    Författare :Sergio Ivan Tusso Gomez; Jochen B.W. Wolf; Simone Immler; Roger K. Butlin; Uppsala universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; adaptation; divergence; selection; experimental evolution; genomics; genome evolution; population genetics; fission yeast; phenotypic variation; Biology with specialization in Evolutionary Genetics; Biologi med inriktning mot evolutionär genetik;

    Sammanfattning : How adaptation and population differentiation occur is fundamental to understand the origin of biodiversity. Work in speciation alongside the increased ease of generating genomic data have allowed the exploration of genomic changes relevant to adaptation. LÄS MER

  3. 2. Skeletal muscle fiber types in man : With special reference to anabolic signaling and mitochondrial bioenergetics

    Författare :Sebastian Edman; William Apro; Filip J Larsen; Abram Katz; Leigh Breen; Gymnastik- och idrottshögskolan; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; mTORC1; THRIFTY; fiber type identification; muscle growth; aging; sarcopenia; mitochondrial function; oxphos; metabolism; Medicin Teknik; Medicine Technology;

    Sammanfattning : Human skeletal muscle consists of a mixture of slow-twitch (type I) and fast-twitch (type II) fibers. The type I fibers are endurance-oriented, with a metabolic system and infrastructure that supports aerobic metabolism. LÄS MER

  4. 3. Islet hormonal hypersecretion and metformin’s effect on islet hormonal secretion studied in vitro and in vivo

    Författare :Quan Wen; Anders Forslund; Hannes Manell; Hjalti Kristinsson; Lisa Juntti-Berggren; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; alpha cell; carboxypeptidase E; childhood obesity; DRP-1; free fatty acids; glucagon secretion; glucose metabolism; glucose stimulated insulin secretion; human islets; hyperinsulinemia; metformin; mitochondrial fission; oral glucose tolerance test OGTT ; prohormone convertase; proinsulin; proinsulin to insulin ratio PI:I ;

    Sammanfattning : Childhood obesity has surged globally. Elevated levels of free fatty acids contribute to hyperinsulinemia, hyperproinsulinemia, and hyperglucagonemia connected with both obesity and type 2 diabetes mellitus (T2DM). Metformin has beneficial effects on islets by influencing metabolism and reducing stress-induced cell death. LÄS MER

  5. 4. Characterization of mitochondrial membrane proteins as novel components in mitochondrial dynamics

    Författare :Tong Liu; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Mitochondria are dynamic organelles that frequently change their shape by shifting the balance of fusion and fission in response to cellular metabolic needs. This process is termed mitochondrial dynamics. Dysregulation of mitochondrial dynamics has been described in many human diseases. LÄS MER

  7. 5. Molecular mechanisms of human mitochondrial dynamics : inspiration and challenge

    Författare :Rong Yu; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Mitochondria are highly dynamic organelles in cells. They frequently change the morphology via continuous fission and fusion events, referred to as mitochondrial dynamics, which includes the shape, size and number of mitochondria in the cell, as well as mitochondrial subcellular distribution and mitochondrial quality control. LÄS MER