Sökning: "mTORC1"

Visar resultat 1 - 5 av 22 avhandlingar innehållade ordet mTORC1.

  1. 1. Characterization of Amino Acid Transporters Transporters expressed in the central nervous system belonging to the Solute Carrier family SLC38

    Detta är en avhandling från Uppsala : Acta Universitatis Upsaliensis

    Författare :Sofie Victoria Hellsten; Uppsala universitet.; [2016]
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Solute carriers; amino acid transporter; SLC38 family; SLC38A8; SNAT8; SLC38A10; SNAT10; SLC38A9; SNAT9; amino acid starvation; AAR; mTORC1; Neuroscience; Neurovetenskap;

    Sammanfattning : In cells and organelles transporters are responsible for translocation of amino acids, sugars and nucleotides among others. In the central nervous system (CNS), amino acid transporters can function as neurotransmitter transporters and nutrient sensors. LÄS MER

  2. 2. Signaling pathways in the development of female germ cells

    Detta är en avhandling från Umeå : Umeå universitet

    Författare :Deepak Adhikari; Umeå universitet.; [2014]
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; ovary; primordial follicle; activation; mTORC₁; PI₃K; oocyte maturation; MPF; Cdk₁; medicinsk biokemi; Medical Biochemistry;

    Sammanfattning : Primordial follicles are the first small follicles to appear in the mammalian ovary. Women are born with a fixed number of primordial follicles in the ovaries. Once formed, the pool of primordial follicles serves as a source of developing follicles and oocytes. LÄS MER

  3. 3. Characterization of Centrally Expressed Solute Carriers Histological and Functional Studies with Transgenic Mice

    Detta är en avhandling från Uppsala : Acta Universitatis Upsaliensis

    Författare :Sahar Roshanbin; Uppsala universitet.; [2016]
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; SLC; Solute carriers; Amino acid transporter; PAT; B0AT2; mTORC1; Medical Science; Medicinsk vetenskap;

    Sammanfattning : The Solute Carrier (SLC) superfamily is the largest group of membrane-bound transporters, currently with 456 transporters in 52 families. Much remains unknown about the tissue distribution and function of many of these transporters. LÄS MER

  4. 4. Effects of exercise and amino acid intake on mechanisms regulating protein synthesis and breakdown in human muscle

    Detta är en avhandling från Stockholm : Gymnastik- och idrottshögskolan

    Författare :Marcus Moberg; GIH. Gymnastik- och idrottshögskolan; [2016]
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Resistance exercise; concurrent exericse; leucine; BCAA; mTORC1 signaling; protein synthesis; MuRF-1; PGC-1alpha; Medicin Teknik; Medicine Technology;

    Sammanfattning : Skeletal muscle adapts differently to specific modes of exercise, where resistance training results in muscle growth and endurance training induces mitochondrial biogenesis. These are results of molecular events that occur after each exercise session, increasing the expression of specific genes and the rate of both synthesis and breakdown of protein. LÄS MER

  5. 5. Molecular mechanisms of ovarian follicular development and early embryogenesis

    Detta är en avhandling från Stockholm : Gymnastik- och idrottshögskolan

    Författare :Nagaraju Gorre; Göteborgs universitet.; Gothenburg University.; [2014]
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; ovary; primordial follicles; Embryogenesis; PI3K-mTORC1 signaling;

    Sammanfattning : In the mammalian ovary, the dormant primordial follicles are the source of developing follicles and fertilizable ova for the entire reproductive life. In addition, the duration of fertility of a female is determined by the initial size of her pool of primordial follicles and by the rate of its activation and depletion. LÄS MER