Sökning: "genome evolution"

Visar resultat 1 - 5 av 319 avhandlingar innehållade orden genome evolution.

  1. 1. Modeling Genome Evolution : Creation, Change and Destruction

    Författare :Mats Pettersson; Otto Berg; Paul Sniegowski; Uppsala universitet; []
    Nyckelord :Molecular biology; Theotretical biology; Population genetics; Stochastic modeling; Genome evolution; Molekylärbiologi;

    Sammanfattning : Historically, evolution has been studied either by looking at morphological traits in living organisms and the fossil record, or by using bioinformatics and comparative genomics. While highly useful for deducing evolutionary history, these approaches are not particularly well suited for studying the mechanisms of evolution. LÄS MER

  3. 2. Biased Evolution : Causes and Consequences

    Författare :Gerrit Brandis; Diarmaid Hughes; Erik Böttger; Uppsala universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Evolution; Codon usage bias; Post-transcriptional regulation; Recombination; Inversion; EF-Tu; Frameshift suppression; Antibiotic resistance; Rifampicin; Ciprofloxacin; Compensatory evolution; Drug efflux; RNA polymerase; DNA gyrase; Mikrobiologi; Microbiology;

    Sammanfattning : In evolution alternative genetic trajectories can potentially lead to similar phenotypic outcomes. However, certain trajectories are preferred over others. These preferences bias the genomes of living organisms and the underlying processes can be observed in ongoing evolution. LÄS MER

  4. 3. Expanding the Chlamydiae tree : Insights into genome diversity and evolution

    Författare :Jennah E. Dharamshi; Thijs J. G. Ettema; Alexander Probst; Uppsala universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; PVC superphylum; Chlamydiae; chlamydia; intracellular; symbiosis; endosymbiont; pathogen; marine sediment; sponge microbiome; metagenomics; uncultured microbial diversity; phylogenomics; microbial evolution; eukaryote evolution; Biologi med inriktning mot molekylär evolution; Biology with specialization in Molecular Evolution;

    Sammanfattning : Chlamydiae is a phylum of obligate intracellular bacteria. They have a conserved lifecycle and infect eukaryotic hosts, ranging from animals to amoeba. Chlamydiae includes pathogens, and is well-studied from a medical perspective. LÄS MER

  5. 4. Genome Evolution and Host Adaptation in Bartonella

    Författare :Eva Caroline Berglund; Siv GE Andersson; Brendan Wren; Uppsala universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Bartonella; genome evolution; genome diversity; phage; gene transfer agent; secretion system; microarray; Bioinformatics; Bioinformatik; Evolutionary Genetics; evolutionär genetik;

    Sammanfattning : Bacteria of the genus Bartonella infect the red blood cells of a wide range of wild and domestic mammals and are transmitted between hosts by blood-sucking insects. Although most Bartonella infections are asymptomatic, the genus contains several human pathogens. LÄS MER

  7. 5. Lifestyle and Genome Evolution in Vector-Borne Bacteria : A Comparison of Three Bartonella Species

    Författare :Anna Carolin Frank; Siv Andersson; Stewart Cole; Uppsala universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Biology; Bartonella; evolution; host-restriction; vector-borne; horizontal gene transfer; genome reduction; alpha-proteobacteria; Type-IV secretion; Biologi; Biology; Biologi;

    Sammanfattning : Bacterial genomes provide records of the molecular processes associated with emergence and evolution of different bacterial lifestyles. This thesis is based on whole-genome comparisons within the genus Bartonella, an excellent model system for studies of host- and vector-specificity and infection outcome in animal-associated bacteria. LÄS MER