Sökning: "lipoprotein"

Visar resultat 36 - 40 av 316 avhandlingar innehållade ordet lipoprotein.

1. 36. Low density lipoprotein (LDL) heterogeneity : implications for cardiovascular disease and genetic influence

   Författare :Camilla Skoglund Andersson; Karolinska Institutet; Karolinska Institutet; []
   Nyckelord :Low density lipoprotein; gradient gel electrophoresis; intima-media thickness; atherosclerosis; myocardial infarction; low density lipoprotein oxidation; cholesteryl ester transfer protein; lipoprotein lipase; hepatic lipase; apolipoprotein E; apolipoprotein B; microsomal triglyceride transfer protein; genetics; lipoproteins; metabolism;

   Sammanfattning : The low density lipoprotein (LDL) particle population is heterogeneous with regard to several structural and functional properties that may influence its atherogenic potential. A preponderance of small, dense LDL is associated with an increased risk of coronary heart disease (CHD), and also predicts future CHD events. LÄS MER

3. 37. Cytokines and lipids in pregnancy – effects on developmental programming and placental nutrient transfer

   Författare :Susanne Lager; Göteborgs universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; adipose tissue; amino acids; cytokines; developmental programming; free fatty acids; insulin resistance; interleukin-6; lipoprotein lipase; nutrient transport; placenta; toll-like receptor 4;

   Sammanfattning : Metabolic disturbances, in particular those associated with nutritional challenges, that take place during development, both in utero and early postnatal life, have long-lasting health consequences on an individual. The most pronounced evidence of these challenges is a deviation in birth weight. LÄS MER

4. 38. Glucose and lipid metabolism in insulin resistance : an experimental study in fat cells

   Författare :Jonas Burén; Umeå universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Public health; adipocyte; insulin resistance; type 2 diabetes; insulin signalling; glucose uptake; insulin; glucose; dexamethasone; insulin receptor substrate; protein kinase B; GLUT4; lipoprotein lipase; Folkhälsomedicin; Public health medicine research areas; Folkhälsomedicinska forskningsområden; medicin; Medicine;

   Sammanfattning : Type 2 diabetes is usually caused by a combination of pancreatic β-cell failure and insulin resistance in target tissues like liver, muscle and fat. Insulin resistance is characterised by an impaired effect of insulin to reduce hepatic glucose production and to promote glucose uptake in peripheral tissues. LÄS MER

5. 39. Effects of prolactin on metabolism - changes induced by hyperprolactinemia

   Författare :Louise Nilsson; Göteborgs universitet; []
   Nyckelord :prolactin; prolactin receptor; hyperprolactinemia; adipose tissue; lipoprotein lipase; malonyl-CoA; glucose transporter 4; retinol-binding protein 4; adiponectin; lipid oxidation;

   Sammanfattning : High prolactin levels during breast-feeding, is recognized to influence metabolism in order to supply glucose and fat for milk production. Pathologic overproduction of prolactin, hyperprolactinemia, is a condition primarily associated with reproductive disorders; however, the metabolic impact of elevated prolactin indicates that these parameters might be considered in clinical management of the condition. LÄS MER

7. 40. Growth hormone and PPARa in the regulation of lipoprotein metabolism

   Författare :Daniel Lindén; Göteborgs universitet; []
   Nyckelord :growth hormone; insulin; fatty acids; PPARa; apolipoprotein B; VLDL; mRNA editing;

   Sammanfattning : In humans, apolipoprotein B (apoB)-100 is produced in the liver and apoB-48 is formed in the intestine. In the rat, however, the two forms of apoB are produced in the liver, leading to the formation of VLDL consisting of either apoB-48 or apoB-100. LÄS MER