Sökning: "toll-like receptor 4"

Visar resultat 1 - 5 av 48 avhandlingar innehållade orden toll-like receptor 4.

  1. 1. Renal failure in experimental sepsis: role of Endothelin and the Toll-like receptor 4

    Detta är en avhandling från Stockholm : Karolinska Institutet, Dept of Clinical Science, Intervention and Technology

    Författare :Johan Fenhammar; Karolinska Institutet.; Karolinska Institutet.; [2011]

    Sammanfattning : Sepsis is the leading cause of renal failure in critically ill patients, but the pathogenesis of septic kidney dysfunction is poorly defined. The current paradigm states that hypoperfusion and excessive renal vasoconstriction results in renal ischemia. LÄS MER

  2. 2. Effects of Inflammatory Mediators on Pulmonary Airways

    Detta är en avhandling från Medicinska fakulteten, Lunds universitet

    Författare :Ofir Bachar; [2007]
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; electric ?eld stimulation; bradykinin; airway; tumor necrosis factor a; Respiratory system; nitric oxide; Andningsorganen; Toll-like receptor; prostaglandin E2; neurotrophin; allergy;

    Sammanfattning : Chronic inflammation is together with excessive contraction of the airways key features of asthma. The aims of the thesis were to analyze the effect of inflammatory mediators on airway smooth muscle, using an in vitro model of cultured murine airways. LÄS MER

  3. 3. Platelets in inflammation Role of complement protein C1q, C-reactive proteinand toll-like receptors

    Detta är en avhandling från Linköping : Linköping University Electronic Press

    Författare :Caroline Skoglund; Torbjörn Bengtsson; Jonas Wetterö; Pentti Tengvall; David Erlinge; [2010]

    Sammanfattning : Platelets are proven essential in haemostasis, however, they are now also increasingly recognized as cells with important immunomodulatory properties, e.g. through interaction with leukocytes and several species of bacteria and by release inflammatory mediators upon activation. LÄS MER

  4. 4. Role of TLR4 in Escherichia coli urinary tract infection

    Detta är en avhandling från Division of Microbiology, Immunology and Glycobiology - MIG, Lund Unviersity

    Författare :Patrik Samuelsson; [2004]
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; mykologi; virologi; mycology; Mikrobiologi; bakteriologi; serologi; transplantation; Microbiology; virology; bacteriology; Immunologi; serology; Immunology; Pathogen; Mucosa; P-fimbriae; Toll like receptor;

    Sammanfattning : In this thesis we have used P fimbriated E. coli as a model to investigate the mechanisms of bacterial recognition and cell activation by the urinary tract (UT) epithelium. We show that Toll like receptor 4 (TLR4) is crucial for the recognition and host response to P fimbriated E. coli. LÄS MER

  5. 5. Early-life gut microbiota and breast milk oligosaccharides in relation to childhood immune maturation and allergy

    Detta är en avhandling från Stockholm : Wenner-Gren Institute for Experimental Biology, Stockholm University

    Författare :Ylva Margareta Sjögren; Eva Sverremark-Ekström; Outi Vaarala; [2009]
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; allergy; infant; gut microbiota; human milk oligosaccharides; Bifidobacterium; Lactobacillus; Bacteroides fragilis; Clostridium difficile; family size; secretory IgA; toll like receptor; NATURAL SCIENCES Biology Cell and molecular biology Immunology; NATURVETENSKAP Biologi Cell- och molekylärbiologi Immunologi; immunologi; Immunology;

    Sammanfattning : Atopic allergy is the most common chronic disease among children in the developed world. This high prevalence could be associated with low microbial exposure. The early gut microbiota appears to be important for immune maturation. LÄS MER