Sökning: "apolipoprotein E"

Visar resultat 1 - 5 av 90 avhandlingar innehållade orden apolipoprotein E.

  1. 1. Glucose, Palmitate and Apolipoprotein CIII-induced Effects on Insulin-Producing β-cells

    Författare :E-ri Maria Sol; Peter Bergsten; Noel Morgan; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Medical cell biology; Medicinsk cellbiologi; medicinsk cellbiologi; Medical Cell Biology;

    Sammanfattning : Background and aims: Type 2 diabetes mellitus results from complex interplay between genetic predisposition and environmental factors that together promote impairment of insulin-producing β-cells. Elevated levels of glucose, fatty acid palmitate and apolipoprotein CIII (apoCIII) are implicated in this process. LÄS MER

  3. 2. Peripheral apolipoprotein E and its emerging role in neurodegenerative disease

    Författare :Andreas Giannisis; Henrietta M. Nielsen; Kim Kultima; Johan Ankarklev; Cheryl Wellington; Stockholms universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Alzheimer’s disease; apolipoprotein E; humanized-liver mice; race; diet; neurokemi med molekylär neurobiologi; Neurochemistry with Molecular Neurobiology;

    Sammanfattning : The human apolipoprotein E gene (APOE) is polymorphic and coding for three common alleles; ε2, ε3, and ε4. Carriers of the ε4 allele are at a higher risk of developing sporadic late-onset Alzheimer’s Disease (AD). This association appears to be influenced by inherited traits, race, and sex. LÄS MER

  4. 3. Apolipoprotein CII, CIII and E : studies on their distribution in serum and their role in the uptake of lipoproteins by reticuloendothelial cells

    Författare :Stefan Gustafson; Uppsala universitet; []
    Nyckelord :MEDICINE; MEDICIN;

    Sammanfattning : .... LÄS MER

  5. 4. Apolipoprotein M – Studies of Structure and Function

    Författare :Josefin Ahnström; Malmö Klinisk kemi; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; signal peptidase; signal peptide; crystallization; Apolipoprotein; lipocalin; HDL; coronary heart disease;

    Sammanfattning : Apolipoprotein M (apoM), a 25 kDa plasma protein, is found in all major lipoprotein classes, although the majority is found in high density lipoproteins (HDL). ApoM has been suggested to be involved in the formation of and adding to the antiatherogenic functions of HDL, but its function is still not completely known. LÄS MER

  7. 5. Cholesterol and apolipoprotein E in suicidal behavior

    Författare :Peter Asellus; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Introduction: Low cholesterol has repeatedly been associated with an increased risk of suicidal and violent behavior. The increase in risk is believed to be associated with alterations in serotonergic signaling, which is associated with low cholesterol. LÄS MER