Sökning: "cholesteryl ester transfer protein"

Hittade 3 avhandlingar innehållade orden cholesteryl ester transfer protein.

  1. 1. Low density lipoprotein (LDL) heterogeneity : implications for cardiovascular disease and genetic influence

    Författare :Camilla Skoglund Andersson; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :Low density lipoprotein; gradient gel electrophoresis; intima-media thickness; atherosclerosis; myocardial infarction; low density lipoprotein oxidation; cholesteryl ester transfer protein; lipoprotein lipase; hepatic lipase; apolipoprotein E; apolipoprotein B; microsomal triglyceride transfer protein; genetics; lipoproteins; metabolism;

    Sammanfattning : The low density lipoprotein (LDL) particle population is heterogeneous with regard to several structural and functional properties that may influence its atherogenic potential. A preponderance of small, dense LDL is associated with an increased risk of coronary heart disease (CHD), and also predicts future CHD events. LÄS MER

  3. 2. Prediction Models and Pharmacogenomics in Adult Growth Hormone Deficiency

    Författare :Edna J L Barbosa; Göteborgs universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; growth hormone deficiency; hypopituitarism; growth hormone replacement therapy; prediction models; candidate gene approach; polymorphisms; body composition; growth hormone receptor; lipid metabolism; extracellular water; pharmacogenomics;

    Sammanfattning : The overall aim of this thesis was to study clinical and genetic factors that influence response to growth hormone replacement therapy (GHRT) in GH deficient (GHD) adults. The patients were part of a cohort of adults with hypopituitarism and severe GHD who were studied before and after 12 months of GHRT. LÄS MER

  4. 3. Fighting cardiometabolic disease : validation of new experimental models and therapeutic targets

    Författare :Mirko Enea Minniti; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : The prevalence of cardiometabolic diseases (CMD) such as atherosclerotic cardiovascular diseases, type 2 diabetes mellitus and nonalcoholic fatty liver disease (NAFLD), has grown dramatically during the last decades. Hence, massive research efforts are allocated to identify the pathophysiological mechanisms and new therapeutic targets for these morbidities. LÄS MER