Sökning: "developmental programming"
Visar resultat 1 - 5 av 27 avhandlingar innehållade orden developmental programming.
1. Cytokines and lipids in pregnancy – effects on developmental programming and placental nutrient transfer
Sammanfattning : Metabolic disturbances, in particular those associated with nutritional challenges, that take place during development, both in utero and early postnatal life, have long-lasting health consequences on an individual. The most pronounced evidence of these challenges is a deviation in birth weight. LÄS MER
2. Perinatal programming and neuroendocrine function
Sammanfattning : Perinatal growth and development are dependent on a sufficient metabolic, hormonal and nutritional environment. Suboptimal conditions during specific perinatal developmental windows can lead to permanent programming of physiological systems in the fetus or newborn, with implications for adult health. LÄS MER
3. Essential fatty acids in the perinatal period. Short and long term effects in a rat model
Sammanfattning : Nutritional factors during a sensitive perinatal period may lead to developmental adaptations proposed to program for pathological conditions later in life. An adequate supply of essential fatty acids (EFA) during pregnancy and lactation is crucial for optimal fetal and postnatal development. LÄS MER
4. Impact of epidemiologically identified mixtures of endocrine disrupting chemicals on metabolic programming
Sammanfattning : We are ubiquitously exposed to a plethora of endocrine-disrupting chemicals (EDCs), i.e. substances that alter the function(s) of the endocrine system. While ample evidence show individual EDC's influence on developmental processes resulting in adverse health outcomes, less is known about the effects of human-relevant EDC mixtures exposure. LÄS MER
5. Single-cell transcriptomic analyses of early embryonic development and developmental programming by androgen excess
Sammanfattning : Infertility is a compelling problem an increased prevalence among couples. Although multiple causes have been hypothesized to increase the risk of infertility, changes in lifestyles and environment are the possible links to the causes. LÄS MER