Sökning: "disulfide stress"

Visar resultat 16 - 20 av 24 avhandlingar innehållade orden disulfide stress.

  1. 16. Exposure, health effects, immunological markers and biomarkers of susceptibility among Swedish rubber workers

    Författare :Lena S Jönsson; Avdelningen för arbets- och miljömedicin; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Yrkesmedicin; arbetsmiljömedicin; industrial medicine; Public health; epidemiology; Folkhälsa; epidemiologi; Occupational health; Andningsorganen; rubber industry; polymorphisms; vulcanisation fumes; Respiratory system; nausea; headache; exposure-response relationships; biomarkers; symptoms; airways; eyes; TTCA; PAH; 1-hydroxypyrene;

    Sammanfattning : Workers in the rubber industry have an increased risk of several diseases, such as airway disease, cancer and probably cardiovascular disease. The exposure is very complex; carbon disulfide (CS2) and polycyclic aromatic hydrocarbons (PAHs) being two of the contaminants. LÄS MER

  2. 17. Optimizing membrane and secretory protein production in Gram-negative bacteria

    Författare :Anna Hjelm; Jan-Willem de Gier; Alex Toftgaard Nielsen; Stockholms universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Biochemistry; biokemi;

    Sammanfattning : Proteins fulfil a wide variety of essential functions in the cell. Recombinant protein production in the Gram-negative bacterium Escherichia coli (E. coli) facilitates structural and functional studies of proteins and it has been instrumental in biotechnology for the manufacturing of e.g. LÄS MER

  3. 18. Structure and function of relaxins

    Författare :Linda M. Haugaard-Kedström; Johan Rosengren; Torleif Härd; Linnéuniversitetet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; relaxin; insulin-like peptide; peptide hormone; peptide synthesis and NMR; Organic Chemistry; Organisk kemi;

    Sammanfattning : The relaxin/insulin superfamily is a group of peptide hormones that consists of ten members in human, namely relaxins 1-3, insulin-like peptides (INSL) 3-6, insulin and insulin-like growth factors (IGF) I-II. These peptides have various functions in the body, such as regulating growth, blood glucose levels,  collagen metabolism, germ cell maturation and appetite. LÄS MER

  4. 19. The role of the DAMP molecule HMGB1 in neuroinflammation and macrophage activation

    Författare :Henna Salo; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : High mobility group box 1 (HMGB1) is a highly conserved nuclear protein expressed in all eukaryotic cells. While its nuclear functions are vital, we know today that HMGB1 also functions as a Damage Associated Molecular Pattern (DAMP). LÄS MER

  5. 20. Exploring vitamin D and steroid hormone receptors – from healthy elderly to prostate cancer cells

    Författare :Maria Araceli Diaz Cruz; Maria Faresjö; Dennis Larsson Dennis Larsson; Johan Staaf; Jönköping University; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; vitamin D; steroid hormone receptors; lifestyle; methylation; SNPs; healthy elderly; prostate cancer cells; crosstalk; PDIA3;

    Sammanfattning : The genetic background together with environmental factors and lifestyle are key contributors to the health of an individual. Genetic background is inherited and irreversible unless mutations occur. However, lifestyle habits (i.e. LÄS MER