Sökning: "vitamin D"

Visar resultat 1 - 5 av 164 avhandlingar innehållade orden vitamin D.

  1. 1. Regulation of Vitamin D 25-hydroxylases : Effects of Vitamin D Metabolites and Pharmaceutical Compounds on the Bioactivation of Vitamin D

    Författare :Maria Ellfolk; Kjell Wikvall; Maria Norlin; Olavi Pelkonen; Uppsala universitet; []
    Nyckelord :MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; CYP2D25; vitamin D 25-hydroxylase; transcriptional regulation; vitamin D; CYP2R1; CYP2J2; CYP27A1; phenobarbital; efavirenz; fibroblast; LNCaP; Pharmaceutical biochemistry; Farmaceutisk biokemi;

    Sammanfattning : A 700bp portion of the promoter of CYP2D25, the porcine microsomal vitamin D 25-hydroxylase was isolated and sequenced. The computer analysis of the sequence revealed the existence of a putative VDRE at 220 bp upstream of the transcription start site. LÄS MER

  2. 2. Aspects of Vitamin D : Prevalence of deficiency and impact on musculoskeletal parameters

    Författare :Anne Björk; Östen Ljunggren; Gunnar Johansson; Andreas Kindmark; Anna Spångeus; Uppsala universitet; []
    Nyckelord :MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Vitamin D; CYP2R1; Vitamin D receptor Gene; Polymorphisms; Muscle Strength; Endokrinologi och Diabetologi; Endocrinology and Diabetology;

    Sammanfattning : Vitamin D is central in calcium turnover, and adequate levels are important for skeletal health. It is not clear how large contributions from food and sunlight are in Swedish primary care patients, considering the low radiation of UVB in Sweden and fortification of some foods, and whether differences exist between patients of immigrant and Swedish origin. LÄS MER

  3. 3. Vitamin D Hydroxylating Enzymes and Analogues in Parathyroid Tumors and Breast Cancer

    Författare :Ulrika Segersten; Gunnar Westin; Per Hellman; Göran Åkerström; Martin Bäckdahl; Uppsala universitet; []
    Nyckelord :MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Surgery; hyperparathyroidism; breast cancer; vitamin D; CYP27B1; CYP24A1; vitamin D analogues; ketoconazole; vitamin D receptor; Kirurgi; Surgery; Kirurgi; Surgery; kirurgi;

    Sammanfattning : In hyperparathyroidism (HPT) raised serum concentrations of ionized calcium is caused by increased secretion of parathyroid hormone (PTH) by parathyroid tumors. Active vitamin D, 1α,25-dihydroxyvitamin D3, is known to suppress PTH secretion and to reduce proliferation of parathyroid tumor cells. LÄS MER

  4. 4. Boning up on Vitamin D : Observational Studies on Bone and Health

    Författare :Greta Snellman; Karl Michaëlsson; Haakon Meyer; Uppsala universitet; []
    Nyckelord :MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Vitamin D; fracture; BMD; assays; genes; mortality; cohort studies; Orthopaedics; Ortopedi;

    Sammanfattning : The primary function of vitamin D in humans is to maintain sufficient circulating calcium concentrations. Low vitamin D levels could result in excessive calcium resorption from bone. Vitamin deficiency may therefore decrease bone mineral density (BMD), resulting in an increased risk of fracture. LÄS MER

  5. 5. Vitamin D and its receptor in parathyroid tumors

    Författare :Pamela Correa; Martin Bäckdahl; Uppsala universitet; []
    Nyckelord :MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Surgery; hyperparathyroidism; loss of heterozygoisty; vitamin D; vitamin D receptor; polymorphism; hydroxylase; genetics; tumorigenesis; Kirurgi; Surgery; Kirurgi; Surgery; kirurgi;

    Sammanfattning : Correa, P. 2002. Vitamin D and its receptor in parathyroid tumors. Acta Universitatis Upsaliensis. LÄS MER