Sökning: "Jan-Willem de Gier"
Visar resultat 1 - 5 av 13 avhandlingar innehållade orden Jan-Willem de Gier.
1. Functional aspects of inorganic phosphate transport
Sammanfattning : Inorganic phosphate is an essential nutrient for all organisms. It is required for many cellular components as nucleic acids and phospholipids, and as energy-carrying compounds such as ATP. Thus, a regulated uptake of this pivotal nutrient is of outermost importance. LÄS MER
2. Protein targeting, translocation and insertion in Escherichia coli : Proteomic analysis of substrate-pathway relationships
Sammanfattning : Approximately 10% of the open reading frames in the genome of the Gram-negative bacterium E. coli encodes secretory proteins, and 20% encodes integral inner membrane proteins (IMPs). LÄS MER
3. Protein production in the E. coli cell envelope
Sammanfattning : Proteins fulfil essential functions in every cell and malfunctioning proteins are often the cause of diseases. On the other hand, proteins like antibody fragments or hormones can be used to treat diseases. LÄS MER
4. GFP as a tool to monitor membrane protein topology and overexpression in Escherichia coli
Sammanfattning : Membrane proteins are essential for life, and roughly one-quarter of all open reading frames in sequenced genomes code for membrane proteins. Unfortunately, our understanding of membrane proteins lags behind that of soluble proteins, and is best reflected by the fact that only 0. LÄS MER
5. Production and folding of proteins in the periplasm of Escherichia coli
Sammanfattning : The Gram-negative bacterium E. coli is the most widely used host for the production of recombinant proteins. Disulfide bond containing recombinant proteins are usually produced in the periplasm of E. coli since in this compartment of the cell - in contrast to the cytoplasm - disulfide bond formation is promoted. LÄS MER