Sökning: "combinatorial selection"
Visar resultat 1 - 5 av 47 avhandlingar innehållade orden combinatorial selection.
1. Selection and use of affinity proteins developed by combinatorial engineering
Sammanfattning : In affinity protein biotechnology the selective bindingbetween a chosen protein and an interacting biomolecule isutilized for a variety of applications including bioseparation,detection and therapy. Traditionally, affinity proteinsrecruited for such applications have been derived from naturalproteins or immunoglobulins generated via immunization routes. LÄS MER
2. Universal Instruction Selection
Sammanfattning : In code generation, instruction selection chooses instructions to implement a given program under compilation, global code motion moves computations from one part of the program to another, and block ordering places program blocks in a consecutive sequence. Local instruction selection chooses instructions one program block at a time while global instruction selection does so for the entire function. LÄS MER
3. Combinatorial Synthesis of Pilicides
Sammanfattning : This thesis describes a combinatorial approach to design and synthesis of three libraries of compounds, referred to as pilicides, designed to target periplasmic chaperones present in uropathogenic Escherichia coli bacteria that are the main cause of urinary tract infections. Periplasmic chaperones are required for assembly of adhesive organelles, i. LÄS MER
4. Selection of Resistance at very low Antibiotic Concentrations
Sammanfattning : The extensive medical and agricultural use and misuse of antibiotics during the last 70 years has caused an enrichment of resistant pathogenic bacteria that now severely threatens our capacity to efficiently treat bacterial infections. While is has been known for a long time that high concentrations of antibiotics can select for resistant mutants, less is known about the lower limit at which antibiotics can be selective and enrich for resistant bacteria. LÄS MER
5. On bacterial formats in protein library technology
Sammanfattning : Millions of years of evolution have resulted in an immense number of different proteins, which participate in virtually every process within cells and thus are of utmost importance for allknown forms of life. In addition, there are several examples of natural proteins which have found use in applications outside their natural environment, such as the use of enzymes infood industry and washing powders or the use of antibodies in diagnostic, bioseparation or therapeutic applications. LÄS MER
