Sökning: "Laura Piddock"

Hittade 2 avhandlingar innehållade orden Laura Piddock.

  1. 1. Selection of Resistance at very low Antibiotic Concentrations

    Författare :Erik Gullberg; Dan I Andersson; Diarmaid Hughes; Linus Sandegren; Laura Piddock; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Antibiotic resistance; Selection; Antibiotic resistant bacteria; Minimal inhibitory concentration; Heavy metals; Conjugative plasmid; ESBL; Mikrobiologi; Microbiology; Biology with specialization in Microbiology; Biologi med inriktning mot mikrobiologi; Biology with specialization in Molecular Evolution; Biologi med inriktning mot molekylär evolution;

    Sammanfattning : The extensive medical and agricultural use and misuse of antibiotics during the last 70 years has caused an enrichment of resistant pathogenic bacteria that now severely threatens our capacity to efficiently treat bacterial infections. While is has been known for a long time that high concentrations of antibiotics can select for resistant mutants, less is known about the lower limit at which antibiotics can be selective and enrich for resistant bacteria. LÄS MER

  3. 2. Mechanisms and Dynamics of Mecillinam Resistance in Escherichia coli

    Författare :Elisabeth Thulin; Dan I Andersson; Laura Piddock; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Mecillinam; Antibiotic resistance; Escherichia coli; Urinary tract infections; Fitness; Penicillin binding proteins; cysteine biosynthesis; Mikrobiologi; Microbiology;

    Sammanfattning : The introduction of antibiotics in healthcare is one of the most important medical achievements with regard to reducing human morbidity and mortality. However, bacterial pathogens have acquired antibiotic resistance at an increasing rate, and due to a high prevalence of resistance to some antibiotics they can no longer be used therapeutically. LÄS MER