Sökning: "allylic substitution"

Visar resultat 1 - 5 av 21 avhandlingar innehållade orden allylic substitution.

1. 1. Transition metal-catalyzed allylic and vinylic functionalization : Method development and mechanistic investigations

   Författare :Johanna M. Larsson; Kálmán J. Szabó; Dennis G. Hall; Stockholms universitet; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; palladium; copper; catalysis; Heck reaction; C-H functionalization; allylic substitution; silylation; borylation; trifluoromethylation; fluorination; mechanistic study; transition metal; alkene; allylic silane; allylic boronate; allylic fluoride; organisk kemi; Organic Chemistry;

   Sammanfattning : The use of small molecule building blocks in, for example, pharmaceutical research and new material development, creates a need for new and improved organic synthesis methods. The use of transition metals as mediators and catalysts opens up new reaction pathways that have made the synthesis of completely new compounds possible as well as greatly improved the synthetic routes to known compounds. LÄS MER

3. 2. Asymmetric Synthesis and Mechanistic Studies on Copper(I)-Catalyzed Substitution of Allylic Substrates

   Författare :Jakob Norinder; Jan-Erling Bäckvall; Norbert Krause; Stockholms universitet; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; copper; allylic substitution; ferrocene; DYKAT; cross-coupling; homo-coupling; DFT; Organic chemistry; Organisk kemi;

   Sammanfattning : This thesis deals with the copper-catalyzed substitution of allylic substrates.In the first part of this thesis, the synthesis of a series of metallocenethiolates is described. The thiolates were examined as ligands in the enantioselective copper(I)-catalyzed γ-substitution of allylic acetates. LÄS MER

4. 3. Palladium-catalyzed aromatic coupling and allylic substitution

   Författare :Helena Hagelin; KTH; []
   Nyckelord :;

   Sammanfattning : Different types of palladium(II)-catalyzed aromatic couplingreactions have been investigated.The cyclization of diphenyl ether was found to be moresensitive to reaction conditions than was the cyclization ofthe diphenylamine derivatives. LÄS MER

5. 4. Investigation of Symmetry and Electronic Effects in Asymmetric Palladium-Catalysed Allylic Substitutions

   Författare :Robert Stranne; KTH; []
   Nyckelord :chiral ligands; catalysis; pseudo-C2; pseudo-meso; pyrrolidines; pyridines; phospholanes; 1; 1-binaphthylazepines; 1.1-binaphthylphosphepines; allylic substitution; palladium;

   Sammanfattning : .... LÄS MER

7. 5. Palladium-Catalyzed Nucleophilic Substitution of Alcohols : Mechanistic Studies and Synthetic Applications

   Författare :Supaporn Sawadjoon; Joseph Samec; Takao Ikariya; Uppsala universitet; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; palladium; nucleophilic substitution; mechanism; Organic Chemistry; Organisk kemi;

   Sammanfattning : This thesis deals with the palladium-catalyzed nucleophilic substitution of π-activated alcohols in which the C–O bond of a non-manipulated hydroxyl group is cleaved. The thesis is divided in two chapters describing two different catalytic systems. LÄS MER