Sökning: "Minimal inhibitory concentration"
Visar resultat 1 - 5 av 8 avhandlingar innehållade orden Minimal inhibitory concentration.
1. Selection of Resistance at very low Antibiotic Concentrations
Sammanfattning : The extensive medical and agricultural use and misuse of antibiotics during the last 70 years has caused an enrichment of resistant pathogenic bacteria that now severely threatens our capacity to efficiently treat bacterial infections. While is has been known for a long time that high concentrations of antibiotics can select for resistant mutants, less is known about the lower limit at which antibiotics can be selective and enrich for resistant bacteria. LÄS MER
2. Biological and Pharmacological Factor that Influence the Selection of Antibiotic Resistance
Sammanfattning : Antibiotic treatment causes an ecological disturbance on the human microflora. Four commensal bacteria: E. coli, enterococci, a-streptococci and coagulase-negative staphylococci, from patients with extensive, high antibiotic usage were investigated with regard to resistance pattern and mutation frequency. LÄS MER
3. Chlamydia pneumoniae in Aortic Valve Sclerosis and Thoracic Aortic Disease : Aspects of Pathogenesis and Therapy
Sammanfattning : The obligate intracellular bacterium Chlamydia pneumoniae (Cp), a common human pathogen, has been associated with atherosclerotic cardiovascular disease. The aetiology of non-rheumatic aortic valve sclerosis has, however, not been clarified. LÄS MER
4. Beta-Lactamase in Haemophilus ducreyi: Purification, Characterization, and Mutagenesis
Sammanfattning : Chancroid caused by Haemophilus ducreyi, has been described as a significantly predisposing factor of HIV heterosexual transmission in an endemic region of both diseases. Antibiotic resistances are extensively found in H. ducreyi and many of the resistances are due to the presence of resistance plasmids. LÄS MER
5. Antibiotic interactions and selection for resistance in biofilms
Sammanfattning : The challenges posed by antibiotic-resistant bacteria in treating infections, particularly those associated with biofilms, require a deeper understanding of this lifestyle and its connection to resistance selection. Additionally, gaining insights into drug interactions is crucial for enhancing combination treatment efficacy and mitigating resistance development. LÄS MER