Sökning: "collagen"

Visar resultat 11 - 15 av 519 avhandlingar innehållade ordet collagen.

  1. 11. Immunomodulation of collagen-induced arthritis

    Författare :Lars Mattsson; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :autoimmunity; arthritis; collagen type II; immunomodulation; vitamin D; parasite;

    Sammanfattning : Collagen-induced arthritis (CIA) is an experimental autoimmune disease sharing many features with human rheumatoid arthritis (RA). CIA development is dependent on T-cells but anti-collagen type II (anti-CII) antibody production by B-cells is also important. LÄS MER

  3. 12. Tumor Stroma in Anaplastic Thyroid Carcinoma : Interstitial Collagen and Tumor Interstitial Fluid Pressure

    Författare :Ellen Lammerts; Lucio Nitsch; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Biochemistry; Collagen I synthesis; Fibrosis; Tumor - stroma interactions; PDGF; TGF-β; Inhibitor; Cell cycle; Tumor growth; Hyaluronan; Biokemi; Biochemistry; Biokemi; Medical Biochemistry; medicinsk biokemi;

    Sammanfattning : Anaplastic thyroid carcinoma (ATC) is an aggressive malignancy in man with stromal fibrosis as one of the main features. Carcinoma cells synthesized no or little collagen I protein. LÄS MER

  4. 13. Dendritic cell presentation of type II collagen

    Författare :Meirav Holmdahl; Lund Dermatologi och venereologi; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Medicin människa och djur ; Medicine human and vertebrates ; chromosome 2; arthritis; proteases; antigen presentation; Dendritic cell; type II collagen;

    Sammanfattning : Type II collagen (CII) is the main protein component of cartilage and immune recognition of CII plays a critical role for the development of collagen induced arthritis (CIA), a widely used animal model for rheumatoid arthritis (RA). Antigen presentation is an important requirement for the immune response, the more efficient presentation of the antigen the better tolerance will be induced and thereby protect against arthritis. LÄS MER

  5. 14. Studies on chondroadherin-an extracellular matrix leucine-rich repeat protein

    Författare :Christina Wenglén; Reumatologi och molekylär skelettbiologi; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Klinisk biologi; Clinical biology; COMP; SLRP; ECM; collagen; cartilage; chondroadherin;

    Sammanfattning : This thesis describes chondroadherin, one of the leucine-rich repeat proteins in the extracellular matrix (ECM) of cartilage. Chondroadherin defines a subgroup of its own by not having an N-terminal extension, having a different cysteine pattern and by being devoid of carbohydrate substitutions. LÄS MER

  7. 15. Collagen Hydrogels for Regenerative Medicine

    Författare :Justina Pupkaite; Peter Påhlsson; Erik Suuronen; May Griffith; Linköpings universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES;

    Sammanfattning : The need for regenerative therapies to repair damaged or deteriorated organs and tissues, such as heart, skin, and cornea, is rising due to donor shortage and aging of the world’s population. Many proposed regenerative therapeutic approaches include a combination of cells, bioactive compounds, and hydrogels. LÄS MER