Sökning: "SLRP"
Hittade 5 avhandlingar innehållade ordet SLRP.
1. Studies on chondroadherin-an extracellular matrix leucine-rich repeat protein
Sammanfattning : This thesis describes chondroadherin, one of the leucine-rich repeat proteins in the extracellular matrix (ECM) of cartilage. Chondroadherin defines a subgroup of its own by not having an N-terminal extension, having a different cysteine pattern and by being devoid of carbohydrate substitutions. LÄS MER
2. Complement in Disease - Extracellular Proteins as Complement Regulators
Sammanfattning : Complement activation occurs during inflammatory joint diseases such as rheumatoid arthritis (RA) and is thought to contribute to the chronic inflammation observed within the joints. Previous studies have shown that certain cartilage components of the small leucine-rich repeat protein (SLRP)-family regulate complement activity, thereby possibly contributing to disease progression. LÄS MER
3. Studies on the extracellular matrix of the dysfunctional pelvic floor
Sammanfattning : Objective: Pelvic floor dysfunction cause impaired quality of life of many women and is one of the most common reasons for gynaecological surgery on benign indications. Little is known about the pelvic floor extracellular matrix as a pre-requisite for mechanical sustainability through vaginal delivery, age and hormonal changes. LÄS MER
4. Towards new therapeutic targets : identification of novel tumor markers in chronic lymphocytic leukemia
Sammanfattning : Chronic Lymphocytic Leukemia (CLL) is the most common leukemia in the Western world and is caused by an abnormal accumulation of B lymphocytes in peripheral blood, bone marrow and lymphoid organs. It is a disease mainly of adults. The clinical outcome of CLL may differ significantly. LÄS MER
5. Stem cells and mineralized tissue : characterization and disease modeling
Sammanfattning : Deficits in mineralized tissue, as a result of abnormal development, trauma, disease or aging, are major medical problems. Consequently, new methods to regenerate stable and functional bone is a main focus in the field of tissue engineering. LÄS MER