Sökning: "collagen"

Visar resultat 16 - 20 av 519 avhandlingar innehållade ordet collagen.

  1. 16. Studies on chondrocyte integrins and mechanical signaling

    Författare :Karin Holmvall; Institutionen för experimentell medicinsk vetenskap; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; teratology; Development biology; collagen; mechnaical stimulation; cartilage; development; chondrocyte; integrin; ontogeny; embryology human ; Utvecklingsbiologi; teratologi; embryologi människa ;

    Sammanfattning : Integrins are a family of cell surface receptors known to bind matrix proteins and to mediate signals such as mechanical signals between the cell and the surrounding matrix. We have studied integrins that are expressed by chondrocytes, with specific focus on the integrins that interact with the cartilage matrix protein collagen type II. LÄS MER

  3. 17. Molecular and microscopical analysis of pathogenic streptococci - studies on surface proteins interacting with human cells and extracellular matrix

    Författare :Marta Bober; Infektionsmedicin; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Streptococcus pyogenes; streptococcal leucine rich repeat protein; M protein; collagen; keratinocytes;

    Sammanfattning : Association to specific host tissue structures allows pathogenic bacteria to establish an infection and facilitates the spread within its host. Interactions between bacterial surface structures and human proteins might determine the outcome of the infection. Streptococcus pyogenes (S. LÄS MER

  4. 18. Cellular Interactions with Extracellular Matrix During Development and in Muscle Disease

    Författare :Carl-Fredrik Tiger; Anders Aspberg; Uppsala universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Cell and molecular biology; integrin; laminin; collagen; muscle; tendon; skeleton; mouse; human; development; Cell- och molekylärbiologi; Cell and molecular biology; Cell- och molekylärbiologi; molekylär cellbiologi; Molecular Cellbiology;

    Sammanfattning : The formation and maintenance of tissues in multicellular animals are crucially dependent on cellular interactions with the extracellular matrix (ECM). Two different studies on such interactions are presented herein. LÄS MER

  5. 19. Vascular remodelling and circulating basement membrane fragments in abdominal aortic aneurysm

    Författare :Mari Holsti; Malin Sund; Anders Wanhainen; Joakim Nordanstig; Umeå universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; AAA; extracellular matrix; vascular remodelling; collagen; inflammation; Surgery; kirurgi;

    Sammanfattning : An abdominal aortic aneurysm (AAA) is a degenerative disease, characterized by advanced inflammation and extracellular matrix (ECM) remodelling. Enhanced protease activity mediated by cytokines results in the degradation of ECM proteins, leading to the generation of different bioactive fragments. LÄS MER

  7. 20. Fibromodulin and chondroadherin in connective tissue homeostasis

    Författare :Viveka Tillgren; Reumatologi och molekylär skelettbiologi; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Collagen; integrin; cell surface proteoglycan; extracellular matrix; and small leucine-rich repeat proteoglycan.;

    Sammanfattning : Connective tissue contains a prominent extracellular matrix (ECM), which provides for physiological and mechanical properties. Intra- and inter-molecular interactions between proteins in this ECM provide for the formation of molecular networks. These interactions determine the shape of the tissue as well as cell behavior. LÄS MER