Sökning: "coiled-coils"

Hittade 5 avhandlingar innehållade ordet coiled-coils.

  1. 1. The Design and Structure Prediction of Protein Oligomers

    Författare :Robert Lizatovic; Biokemi och Strukturbiologi; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; virus capsids; coiled coils; molecular replacement; symmetry; Rosetta; protein design; structure prediction;

    Sammanfattning : The minimum free energy state of a protein (the native state) is encoded by its amino-acid sequence. Due to the many torsional degrees of freedom (DOF) available to a polypeptide chain, a vast number of conformations is possible. LÄS MER

  3. 2. Prediction, Design and Determination of Protein Structures

    Författare :Sebastian Rämisch; Biokemi och Strukturbiologi; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; protein design; Rosetta; Fold-and-Dock; leucine rich repeat proteins; coiled-coils; molecular replacement; ab initio phasing; temperature stability; fluorescent proteins;

    Sammanfattning : The three-dimensional structure of protein is encoded in its amino acid sequence. Modern structure prediction algorithms make it possible to predict the structure of small proteins using sequence information alone. LÄS MER

  4. 3. Light Protection in Plants: Characterisation of Violaxanthin de-epoxidase

    Författare :Erik Hallin; Biokemi och Strukturbiologi; []
    Nyckelord :violaxanthin de-epoxidase; cysteine; disulphide bond; function; pH activation; oligomerisation; circular dichroism; crosslinking; small angle x-ray scattering;

    Sammanfattning : Plants and algae need light to drive the photosynthetic machinery. An excess of light will, however, result in damage to the photosynthetic machinery and to the rest of the organism. The surplus of energy, when exposed to light stress is converted into less harmful heat energy through a process called non-photochemical quenching. LÄS MER

  5. 4. Streptococcal M protein and human C4BP

    Författare :Jenny J Persson; Avdelningen för medicinsk mikrobiologi; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Infektioner; Infections; Medicin människa och djur ; Medicine human and vertebrates ; human C4BP; M protein; antigenic variation; sequence variability; Streptococcus pyogenes; innate immunity;

    Sammanfattning : Antigenic variation of surface proteins allows microorganisms to evade the immune system of the infected host. This phenomenon represents an apparent paradox, because the variable protein must retain an important function, while its antigenic properties vary extensively. LÄS MER

  7. 5. YopD translocator function in Yersinia pseudotuberculosis type III secretion

    Författare :Tiago R. D. Costa; Matthew S. Francis; William D. Picking; Umeå universitet; []
    Nyckelord :Y. pseudotuberculosis; T3SS; translocon; YopD; coiled-coil; effector delivery; regulation; virulence; mikrobiologi; Microbiology;

    Sammanfattning : Type III secretion systems (T3SS) are a common feature of Gram-negative bacteria, allowing them to inject anti-host effectors into the interior of infected eukaryotic cells. By this mechanism, these virulence factors help the bacteria to modulate eukaryotic cell function in its favor and subvert host innate immunity. LÄS MER