Sökning: "virus capsids"
Visar resultat 1 - 5 av 16 avhandlingar innehållade orden virus capsids.
1. Control of Quasi-Equivalence in Virus Capsids
Sammanfattning : Many T=3 plant and insect viruses use a molecular switch in form of order/disorder of a segment of the polypeptide chain to regulate the quasi-equivalent contacts. The structure of a mutant of the T=3 capsid of bacteriophage fr confirms that this virus and other members of the Leviviridae family lack a switch mechanism. LÄS MER
2. Exploring the Molecular Dynamics of Proteins and Viruses
Sammanfattning : Knowledge about structure and dynamics of the important biological macromolecules — proteins, nucleic acids, lipids and sugars — helps to understand their function. Atomic-resolution structures of macromolecules are routinely captured with X-ray crystallography and other techniques. LÄS MER
3. Structural Decorations in Viruses : Unraveling Acquired Functional Structures in Icosahedral RNA Virus Capsids
Sammanfattning : Viruses have a profound impact worldwide, posing challenges to animal welfare, agriculture, human health, and the ecosystem. This thesis examines the realm of non-enveloped icosahedral double-stranded (ds)RNA and single-stranded (ss)RNA viruses through three studies. LÄS MER
4. The Design and Structure Prediction of Protein Oligomers
Sammanfattning : The minimum free energy state of a protein (the native state) is encoded by its amino-acid sequence. Due to the many torsional degrees of freedom (DOF) available to a polypeptide chain, a vast number of conformations is possible. LÄS MER
5. Protein adaptability involved in self-assembled icosahedral capsids
Sammanfattning : Interactions between viral coat proteins determine the size and shape of the virus capsid. Therefore, the plain closed shell of a spherical virus provides an excellent resource for studying and testing protein-protein interactions so as to reveal the properties that lead to symmetrical capsids or other shapes. LÄS MER