Sökning: "leucine rich repeat proteins"

Visar resultat 1 - 5 av 22 avhandlingar innehållade orden leucine rich repeat proteins.

1. 1. Molecular studies on streptococcal surface proteins

   Författare :Johan Waldemarsson; Avdelningen för medicinsk mikrobiologi; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; nonimmunodominance; vaccine; camouflaging; Streptococcus agalactiae; leucine-rich repeat; Streptococcus pyogenes; alpha; fibrinogen; M protein; surface proteins; Rib;

   Sammanfattning : Streptococcus agalactiae and Streptococcus pyogenes are two related human pathogens causing different diseases. This thesis focuses on a number of surface proteins expressed by S. agalactiae and S. pyogenes and, more specifically, the molecular and biological characterization of these proteins. LÄS MER

3. 2. Prediction, Design and Determination of Protein Structures

   Författare :Sebastian Rämisch; Biokemi och Strukturbiologi; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; protein design; Rosetta; Fold-and-Dock; leucine rich repeat proteins; coiled-coils; molecular replacement; ab initio phasing; temperature stability; fluorescent proteins;

   Sammanfattning : The three-dimensional structure of protein is encoded in its amino acid sequence. Modern structure prediction algorithms make it possible to predict the structure of small proteins using sequence information alone. LÄS MER

4. 3. Studies on chondroadherin-an extracellular matrix leucine-rich repeat protein

   Författare :Christina Wenglén; Reumatologi och molekylär skelettbiologi; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Klinisk biologi; Clinical biology; COMP; SLRP; ECM; collagen; cartilage; chondroadherin;

   Sammanfattning : This thesis describes chondroadherin, one of the leucine-rich repeat proteins in the extracellular matrix (ECM) of cartilage. Chondroadherin defines a subgroup of its own by not having an N-terminal extension, having a different cysteine pattern and by being devoid of carbohydrate substitutions. LÄS MER

5. 4. Complex Formation in the Extra Cellular Matrix- Structural Study of CTLD of Agrrecan, Tenascin-R and Chondroadherin

   Författare :Anna Pramhed; Biokemi och Strukturbiologi; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; aggrecan; ECM; fibulin; structure; tenascin; CHAD; chondroadherin; X-ray; crystallography; calcium; CTLD; C-type lectin; fibronectin; FnIII; LRR; epidermal growth factor; leucine-rich repeat; matrix; EGF; cbEGF;

   Sammanfattning : The cells of higher organisms exist in a complex protein network, the extracellular matrix (ECM), which has a wide variety of different components such as glycoproteins, proteoglycans and carbohydrates. As well as being the physical scaffold on which the cells are dependent for their positioning and mobility, the ECM exercises control over the cells, and changes in the matrix will affect the adhesion, proliferation and differentiation properties of these cells. LÄS MER

7. 5. The Identification and Characterisation of LRIG Gene Family and Its Expression in Astrocytic Tumours

   Författare :Dongsheng Guo; Tomas Ekström; Umeå universitet; []
   Nyckelord :astrocytoma; brain; EGFR; LRIG; leucine-rich repeat; real-time RT-PCR; onkologi; Oncology;

   Sammanfattning : Gliomas are the most common primary brain tumours, and their capacity to invade surrounding normal brain prevents complete removal of the tumour. Malignant glioma has still a poor prognosis. However, with the rapid development of molecular biology our understanding about glioma has increased dramatically. LÄS MER