Sökning: "cholinergic system"

Visar resultat 1 - 5 av 94 avhandlingar innehållade orden cholinergic system.

  1. 1. Effects of Orexins, Guanylins and Feeding on Duodenal Bicarbonate Secretion and Enterocyte Intracellular Signaling

    Författare :Magnus Wilhelm Bengtsson; Gunnar Flemström; Olof Nylander; Karl E. O. Åkerman; Per M. Hellström; Uppsala universitet; []
    Nyckelord :Physiology; alkaline secretion; carbohydrates; central nervous system; cholinergic stimulation; duodenum; enteric nervous system; enterochromaffin cell; fasting; feeding; glucose; guanylyl cyclase C; humans; hypocretin; intra-arterial; in situ; intracerebroventricular; luminal acid; luzindole; orexin-B; SB-334867; Fysiologi;

    Sammanfattning : The duodenal epithelium secretes bicarbonate ions and this is regarded as the primary defence mechanism against the acid discharged from the stomach. For an efficient protection, the duodenum must also function as a sensory organ identifying luminal factors. LÄS MER

  3. 2. Towards Heart Rate Variability Tools in P-Health : Pervasive, Preventive, Predictive and Personalized

    Författare :Farhad Abtahi; Kaj Lindecrantz; Birgitta Janerot Sjöberg; Fernando Seoane; Annette Bruchfeld; Metin Akay; KTH; []
    Nyckelord :TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; Heart Rate Variability; Cholinergic Anti-inflammatory Pathway; Autonomic Nervous System; Vagal activity; Biofeedback; Gamification; Serious Gaming; Inflammatory Markers; Raspberry PI; Medical Technology; Medicinsk teknologi;

    Sammanfattning : Heart rate variability (HRV) has received much attention lately. It has been shown that HRV can be used to monitor the autonomic nervous system and to detect autonomic dysfunction, especially vagal dysfunction. Reduced HRV is associated with several diseases and has also been suggested as a predictor of poor outcomes and sudden cardiac death. LÄS MER

  4. 3. Neonatal Developmental Neurotoxicity of Brominated Flame Retardants, the Polybrominated Diphenyl Ethers (PBDEs)

    Författare :Henrik Viberg; Per Eriksson; Susan Schantz; Uppsala universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Biology; brominated flame retardants; polybrominated diphenyl ethers; PBDE; neonatal; development; neurotoxicity; behaviour; cholinergic system; Biologi; Biology; Biologi;

    Sammanfattning : This thesis examines developmental neurotoxic effects of polybrominated diphenyl ethers (PBDEs), PBDE 99, PBDE 153, and the fully brominated PBDE 209, after exposure during the newborn period in rodents. Our environment contains vast numbers of contaminants, including the flame retardants, PBDEs. LÄS MER

  5. 4. Neurotoxic Effects of Nicotine During Neonatal Brain Development : Critical Period and Adult Susceptibility

    Författare :Emma Ankarberg; Per Eriksson; Richard F. Seegal; Uppsala universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Biology; nicotine; neonatal development; behaviour; nicotinic receptors; susceptibility; cholinergic system; paraoxon; PBDE; Biologi; Biology; Biologi;

    Sammanfattning : This thesis examined neurotoxic effects of nicotine exposure during a defined critical period of neonatal brain development in mice.In our environment there are numerous hazardous contaminants that an individual can be exposed to during its entire lifetime. LÄS MER

  7. 5. Developmental neurotoxicity of persistent and non-persistent pollutants : Behavioral and neurochemical assessments of a perfluorinated compound, pesticides and interaction effects

    Författare :Iwa Lee; Henrik Viberg; Per Eriksson; William Mundy; Uppsala universitet; []
    Nyckelord :Brain; Neonatal; Mixtures; Cholinergic system; Organochlorines; Pyrethroids; Organophosphates; Carbamates; Insecticides; PFCs; PFAAs; PFHxS; Endosulfan; Cypermethrin; Chlorpyrifos; Carbaryl; Biology with specialization in Environmental Toxicology; Biologi med inriktning mot miljötoxikologi;

    Sammanfattning : The focus of this thesis was to investigate developmental neurotoxic effects of different persistent and non-persistent environmental pollutants, alone or in binary mixtures, when exposure occurs during a critical period of brain development, in mice. The compounds investigated included a perfluorinated compound, perfluorohexane sulphonate (PFHxS), and four different pesticides, endosulfan, cypermethrin, chlorpyrifos and carbaryl. LÄS MER